Gene Details:

Gene ID Chr. No. Start Position End Position Function View on
Vu_00758 LG1 10923721 10932842 PREDICTED: serine/threonine-protein kinase TOUSLED isoform X2
Map

Annotations  
category   relationship type   keyword
Biological Process   involved in   regulation of post-transcriptional gene silencing by RNA, regulation of post-transcriptional gene silencing by RNA, peptidyl-serine phosphorylation, intracellular signal transduction, peptidyl-serine phosphorylation, peptidyl-serine phosphorylation, chromosome segregation
Cellular Component   is active in   nucleus
Cellular Component   located in   nucleus, nucleus, nucleus, cytoplasm, nucleus
Molecular Function   enables   protein serine/threonine kinase activity, protein binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, protein serine/threonine kinase activity, identical protein binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, protein binding
Pathway   B 09181 Protein families: metabolism   C 01001 Protein kinases [BR:ko01001]
SNP Position Effect Amino acid change
C/G 10923740 5_prime_UTR_premature_start_codon_gain_variant
G/A 10923744 5_prime_UTR_variant
G/C 10923852 5_prime_UTR_premature_start_codon_gain_variant
A/T 10923857 5_prime_UTR_variant
T/A 10923889 5_prime_UTR_variant
T/C 10923921 5_prime_UTR_variant
T/C 10923938 5_prime_UTR_variant
T/C 10923957 5_prime_UTR_variant
T/A 10924337 intron_variant
C/A 10924353 intron_variant
G/A 10924434 intron_variant
A/C 10924454 5_prime_UTR_variant
T/C 10924526 synonymous_variant p.Pro22Pro
T/A 10924667 synonymous_variant p.Thr69Thr
A/T 10924704 intron_variant
C/A 10924707 intron_variant
G/A 10924739 intron_variant
G/T 10924807 intron_variant
A/G 10924864 intron_variant
T/C 10924895 intron_variant
C/A 10925120 synonymous_variant p.Gly97Gly
T/A 10925126 synonymous_variant p.Thr99Thr
T/C 10925195 intron_variant
T/C 10925269 intron_variant
C/A 10925333 intron_variant
T/G 10925334 intron_variant
G/A 10925400 missense_variant p.Val119Met
T/C 10925419 missense_variant p.Ile125Thr
T/C 10925503 missense_variant p.Ile153Thr
T/C 10925558 synonymous_variant p.Asn171Asn
T/G 10925602 intron_variant
C/G 10925608 intron_variant
A/T 10925637 intron_variant
T/A,C 10925770 intron_variant
C/A 10925843 intron_variant
T/G 10925853 intron_variant
G/A 10925857 intron_variant
A/G 10925867 intron_variant
C/A 10925902 intron_variant
T/A 10925907 intron_variant
C/A 10925928 intron_variant
G/A 10926008 intron_variant
T/C 10926037 intron_variant
G/A 10926134 intron_variant
A/G 10926139 intron_variant
T/A 10926143 intron_variant
T/C 10926232 intron_variant
C/A 10926255 intron_variant
T/A 10926332 intron_variant
C/T 10926378 splice_region_variant&synonymous_variant p.Asp176Asp
C/T 10926424 synonymous_variant p.Leu192Leu
A/G 10926473 missense_variant p.Gln208Arg
C/T 10926498 intron_variant
T/C 10926525 intron_variant
A/C 10926527 intron_variant
C/G 10926533 intron_variant
T/G,* 10926565 intron_variant
T/G 10926567 intron_variant
T/G 10926569 intron_variant
G/A 10926593 intron_variant
A/G 10926597 intron_variant
G/A 10926598 intron_variant
C/A 10926640 intron_variant
G/A 10926676 intron_variant
A/G 10926749 intron_variant
T/G 10926760 intron_variant
G/T 10926794 intron_variant
G/T 10926800 intron_variant
A/G 10926919 intron_variant
A/T 10926990 intron_variant
G/T 10926996 intron_variant
T/A 10927014 intron_variant
G/A,* 10927019 intron_variant
G/C 10927039 intron_variant
G/A 10927043 intron_variant
C/T 10927086 intron_variant
G/A 10927089 intron_variant
A/T 10927144 intron_variant
T/G 10927170 intron_variant
A/G 10927171 intron_variant
A/G 10927201 intron_variant
A/G 10927221 intron_variant
T/G 10927393 intron_variant
C/T 10927409 intron_variant
A/G 10927425 intron_variant
A/G 10927467 intron_variant
T/C 10927483 intron_variant
A/T 10927507 intron_variant
A/T 10927564 intron_variant
A/G 10927578 intron_variant
C/T 10927583 intron_variant
A/T 10927679 intron_variant
A/G 10927922 missense_variant p.Ile231Val
A/T 10927948 synonymous_variant p.Ser239Ser
A/G 10928067 intron_variant
C/T 10928072 intron_variant
A/C 10928090 intron_variant
T/G 10928243 intron_variant
G/T 10928379 intron_variant
C/T 10928381 intron_variant
T/A 10928387 intron_variant
G/A 10928411 intron_variant
A/G 10928482 intron_variant
T/A 10928492 intron_variant
T/A 10928740 intron_variant
T/A 10928802 intron_variant
T/C 10928837 intron_variant
C/A 10928846 intron_variant
T/A 10928860 intron_variant
A/G 10928969 intron_variant
C/G 10928976 intron_variant
G/A 10929263 intron_variant
T/A 10929270 intron_variant
G/C 10929281 intron_variant
T/C 10929288 intron_variant
G/A 10929297 intron_variant
T/A 10929325 intron_variant
A/C 10929392 intron_variant
A/G 10929527 intron_variant
C/A 10929609 intron_variant
G/T 10929622 intron_variant
A/G 10929623 intron_variant
C/T 10929624 intron_variant
T/C 10929634 intron_variant
G/C 10929639 intron_variant
G/A 10929665 intron_variant
A/C 10929716 intron_variant
C/G 10929717 intron_variant
C/G 10929728 intron_variant
C/T,* 10929743 intron_variant
G/A 10929816 intron_variant
C/T 10929865 intron_variant
A/G 10929957 intron_variant
T/C 10929959 intron_variant
C/T 10929960 intron_variant
T/A 10930039 intron_variant
T/A 10930157 intron_variant
T/C 10930454 synonymous_variant p.Leu380Leu
T/C 10930471 synonymous_variant p.Ala385Ala
G/C 10930708 intron_variant
C/T 10930814 intron_variant
C/T 10930887 synonymous_variant p.Cys412Cys
C/G 10930891 missense_variant p.Leu414Val
C/T 10931013 synonymous_variant p.Ile454Ile
A/T 10931102 downstream_gene_variant
T/C 10931163 downstream_gene_variant
T/C 10931165 downstream_gene_variant
T/C 10931364 synonymous_variant p.Phe522Phe
T/A 10931554 downstream_gene_variant
T/A 10931750 downstream_gene_variant
C/T 10931774 downstream_gene_variant
A/G 10932041 downstream_gene_variant
G/T 10932048 downstream_gene_variant
A/T 10932080 downstream_gene_variant
A/T 10932095 downstream_gene_variant
A/T 10932123 downstream_gene_variant
A/T 10932124 downstream_gene_variant
C/T 10932159 downstream_gene_variant
A/T 10932180 downstream_gene_variant
T/A 10932198 downstream_gene_variant
C/A 10932201 downstream_gene_variant
C/G 10932268 downstream_gene_variant
C/A 10932276 downstream_gene_variant
G/C 10932304 downstream_gene_variant
G/C 10932306 downstream_gene_variant
G/C 10932310 downstream_gene_variant
T/G,C 10932321 downstream_gene_variant
C/T 10932367 downstream_gene_variant
G/A 10932460 splice_region_variant&intron_variant
G/A 10932564 3_prime_UTR_variant
T/G,* 10932691 3_prime_UTR_variant
G/A 10932764 3_prime_UTR_variant

View accession wise SNPs


Sequence Details:

Protein Sequence:
>Vu_00758.1
MSDDMLIHFSSNSSNQSDHSLPTKIAKLEARMVGKGSSTSSQQPGWSSVSVPSAGKFVRAVENSAEASTSSDSDDDNGGAFLIQANTSKRQKLQEDGNTSVFESVEVVTDGRQTSLDAVETKMHIEMNRKKHGRGRGSSGSGRGRGSRVNDQIKTLISSPTALTSNGQIDNVYHKDEVASLQAKIVALEEELRKSKQEAVDYQNLTQQLEKEMKEMTDHEQQMKPKRMKVISDLLISVSKAERQEARLKVRQDSLRLGNVGVIRAGTVISETWEDGQALKDLNAQLKQLVETKEAIERQRKLFKKKQSDKGDGTDAEAGLPEDILIHDEIYKCRLASLKREEEIVLRERDRYEIEKGRLIREMKRIRDEDGSRFNNFQILNHRYALLNLLGKGGFSEVYKAFDLVDHRYVACKLHGLNAQWSEEKKQSYIRHAIREYNIHKTLVHRHIVRLWDIFEIDQNTFCTVLEYCSGKDLDAVLKATPILSEREAKVIIVQIFQGLIYMNKRTQKIIHYDLKPGNVLFDELGVAKVTDFGLSKIVEDDVGSQGMELTSQGAGTYWYLPPECFELSKTPLISSKVDVWSAGILYYQMLFGRRPFGHHQTQERILREDTIIKARKVDFPSKPTISNEAKDFIRRCLTYNQAERPDVLTIAQDPYLTFSKK*


CDS Sequence:
>Vu_00758.1
ATGTCAGATGACATGCTCATTCATTTCTCGTCCAACTCTTCAAACCAATCCGATCATTCTCTGCCTACAAAGATTGCAAAGTTGGAAGCTCGTATGGTTGGTAAGGGTTCCTCAACCTCTTCTCAGCAACCAGGTTGGTCCTCTGTGTCTGTTCCTTCGGCTGGGAAATTTGTTCGAGCTGTTGAAAATTCGGCTGAAGCATCCACTTCAAGTGATTCTGATGATGATAATGGTGGGGCATTCTTGATACAAGCCAACACATCGAAGCGACAAAAACTTCAAGAAGATGGCAACACTAGTGTTTTTGAAAGCGTTGAGGTTGTTACTGATGGAAGGCAAACTAGTTTGGATGCCGTGGAGACAAAAATGCACATTGAAATGAATAGAAAGAAACATGGTCGTGGAAGAGGGAGTTCTGGTTCGGGTAGAGGCCGGGGTTCCAGAGTTAATGATCAGATCAAAACACTAATTTCTTCTCCAACTGCTTTGACTTCAAATGGTCAGATCGACAATGTATACCATAAAGACGAGGTTGCATCTTTGCAAGCTAAAATTGTTGCTTTGGAGGAGGAACTGCGGAAATCAAAGCAAGAAGCAGTCGATTATCAGAATCTTACTCAGCAACTAGAAAAGGAAATGAAGGAGATGACTGATCATGAACAACAAATGAAGCCTAAGAGGATGAAAGTAATATCTGACTTGCTGATATCCGTTTCAAAAGCCGAAAGACAAGAAGCAAGACTAAAAGTACGACAAGACTCATTGAGACTTGGAAATGTTGGTGTAATCAGAGCTGGAACTGTCATATCTGAAACCTGGGAAGATGGTCAAGCTTTAAAGGATCTGAATGCCCAGCTTAAACAACTAGTAGAAACCAAGGAGGCAATAGAACGACAGCGCAAATTGTTTAAGAAAAAGCAATCTGATAAGGGTGATGGGACAGATGCAGAGGCTGGATTGCCAGAAGATATTCTAATTCACGATGAAATTTACAAGTGTCGATTAGCTAGTCTTAAAAGAGAAGAGGAGATTGTTTTACGAGAGAGGGATCGGTATGAAATAGAGAAGGGGAGGTTAATTCGTGAGATGAAACGCATACGGGATGAAGATGGTTCACGGTTTAACAACTTTCAGATTTTAAATCATCGTTATGCTCTTCTTAACCTTCTTGGGAAGGGAGGATTCAGTGAGGTGTACAAGGCTTTCGATTTGGTGGACCATAGATATGTTGCTTGCAAACTTCATGGTTTAAATGCTCAATGGAGTGAAGAGAAGAAGCAGAGCTACATACGACATGCAATTCGGGAGTATAATATTCACAAGACTCTTGTACATCGTCACATTGTTCGTTTATGGGACATCTTTGAGATTGATCAGAACACGTTCTGCACTGTTCTAGAGTATTGTAGTGGGAAAGATCTTGATGCTGTTCTTAAAGCAACGCCTATATTATCTGAGAGGGAGGCTAAGGTCATCATAGTTCAGATTTTTCAAGGTCTTATTTATATGAATAAAAGAACACAGAAAATTATCCATTATGATTTGAAGCCTGGAAATGTTCTGTTTGATGAACTTGGTGTTGCCAAAGTGACTGATTTTGGTCTTAGTAAGATAGTGGAGGATGATGTTGGATCCCAAGGTATGGAACTTACGTCCCAGGGAGCTGGAACATATTGGTATTTGCCTCCTGAATGCTTTGAGCTCAGCAAGACACCTCTTATATCATCAAAGGTTGATGTCTGGTCTGCTGGTATTTTGTATTATCAAATGCTCTTTGGCCGACGACCTTTCGGGCATCACCAAACCCAAGAGAGAATACTTCGTGAGGACACAATTATTAAGGCTCGGAAGGTTGACTTTCCTTCTAAACCTACCATTTCTAACGAGGCAAAGGATTTTATCCGAAGGTGTCTAACATATAACCAGGCTGAGAGACCAGATGTGTTAACCATTGCTCAAGACCCATATCTCACTTTCTCAAAGAAGTAA


Promoter Sequence:
>Vu_00758::LG1:10921721-10923721(+)
TGACCTTCTTCCAATCTAATACCTAAATATTTCCACTTAATGTTCACTATTATTGTTATAAAATCTTAACAAAATTAAATTTAAAATACCATTATCATATAACAACAAAATGGGTAAGAGAAAACCACCATCATTCATCACAATAATGCCTAACTAGATTTAAGAAGCACTATACCATATCACATTACATTCAAACACAGTTTTTTGGTGCTCGTCCCTTTTAACTTCTCTTGTATTATTCTCGTGTCCTATACTTTTTTTAACCCACAACAACTCTCAATAAAAGAATCAATTCAAAAAACAAAAAAAATGTTTAATATTTTTTTGTCTCTATATTTAAATACATAATTTAATATATTTTTATTTAGGTTTAAACCCTCCCTTGGTCCTCAAGTTTATATGAAAATCTCAGTTGGGTCCTCAAGTTTTTTTCTGTCTCAATTGGGTCATATTTTTTGTAAAAGTGAGCACATTTTGCCATAACCGTTAAGTGTTGTGAGACGGCGTTAAAATGGTGTGAGCTGGATTTTTTCATTTACTGACGTGGCATTGTGCACTAAAATTGAAAGGCCACGTGGTGCCAGATCTTCTCGAAACAGCAGCATCTACTCGGCGCAATGGGCGCGTGCGCATCTTCTCCCTCCGCCAAAACCACCAACACAGCCGTCGCATGGATGAATAATGGCGGTGGCGGTGCACATGCATCGGAATCGTTCCGAAGACCTTCGTCAATCATGGTGATGAACCTGGCGGGTCGAATCTTCTTCCTGGCCGAATCTACTTCCTCGTCCCTCTCTCGCATTCTCATTCCCCCTTGTCCCTCACTCTCCTCTGCGATCTTGCCGTTAAAGCCGGTTCCGCACTGTCCAATCCCAAAAATAACCACACCGGCACAAACAGAGCTTCCGTTAAGCGGCGCCTTTAGACTCGGTGTAAGTTAGTTTTGTTAAAACTGTTTTGGTTTGTTGGGTTTGATTTGTGATTCAATCGATTTGCTTGAGTGGGACCTTGTAAGAGAATAAGAAGAGATTGGTGATTAAATTTGTACTGGTAAGGGCCCAAATGAGAGTGATTGGTTGTGAAAGAAGAGATTGTGAATTGGTATGGCTGCCCCCACAGGAATGATGAAATGCAGCATCTGAACAATTCCCTGCCTTTCTCACAATTCTCCATCTCTGTTTGTTTGTAATTGCACCCATTCTGTTCAAAACATGTACTACGTGAATCAGGGTTCCAGCTTTTGGAATTCAGTGAATTTTTTTGTTTCTTTCTTACAAAACCTTTTTTCAAGGTTTTCCAATACGCGATTAGGGTTGGAAAATTGCGCCGAGTAGATGCGCAGAGGGGGAGGGAGGAGAAGATCTGGCACCACGTGGCCTTTCAATTTTAATGCACAATGTCACGTCAGTAAATGAAAAAATCCAGCTCACACCATTTTAACGCCGTCTCACAACACTTAACGGTTATGGCAAAATGTGCTCACTTTTACAAAAAATATGACCCAATTGAGACAGAAAAAAACTTGAGGACCCAACTGAGATTTTCATATAAACTTGAGGACCAAGGGAGGGTTTAAACCTTTTATTTATTTCTTATTGAATGTGGTTGTTATATATTTTTTTTAAAAGTTAATTTGATCCATTCTGTTTTCTTTCATTTTATTTTTTTTATTTGATAATAAACACTTAAAAAAGATAGATAATTATATTAACTTATACTATCTCATAATTTTTTAAAGGATTTCAGTGTTGATCTAACAAAAAATAATACATTAAGTTTTTTAAAAAATATAAAAACATTAAAAAATTGAATTCTTCCTTTATATATTAGAAAAAAATATTATTAAGGAAAAAAATTACATTACTCTAGGCCGAGTGGATTCAGTGTCTTTGATGTACCGTGCAGTTGAAGCACTGTGAACAGCTGATTGTATACATGCTTCAGATCTTGCCACATGTCCTTCAAATATAAGTAACGGTCAATGCACTTCTATCCTCCTG


Gene Sequence:
>Vu_00758(+)
GGAACACCCACAAAATAATCAGCGGGACAATGTACATTTGCATTTGATTTTAAAACACAGCAACTAAATTATTACATTTCTCAACTGAAAATGTAGAATTTCTCCGAGAAGATCATGAGATTGACTTGGAGGTGATAAAATGAGAGTATTTGTAGGTAAAAAGTATCTTAGGACACATGGCAAAATCTGAAGCATTTATGTAAAATCAAATGGTTCATAGTGTCTCAATTGCATGGTGAAGTTTCTGGGTTAAAGTCACTGAATTACTCCCTACTATCTCTCCTGTTATTTGCAGTCATGCCTTTTTCTTTCACTTCCCCTGTGTTCATTCATTCTTCCCTCCTAATCTTTTGATTATTTCACCACTTTCCCAAACAGCAAAACCCTAGATTCTCTATTTCGCTTAATTCTCTGAGTTCTGCACCCAAAAGGCAGAATATACTCAAAATTTCCCAAAGTTTCATTTTTTTTTCTTTCAATCACATCGGCGTCTCAGTTCTCTGATCACCTTATTTCTTGAACTGTTTCTGCCGTTTTTCCTTTTCATAAACCCCAATTCTTTCACGTGGGTCTGTGGAAAATTGGCATCTTTAGTCACGAATGGGTATGGCCTAGTTCTATTCACCATTTTCCTTTTCCACATTTTCCCCTAAATCGGTTGAATTTTCATTATTGTTGGTTTATCTTGAGGTGAGAAGTTTTTTTTTTCTGTTGCCAATCAGTTTGCAGTTACAGCAACAATGTCAGATGACATGCTCATTCATTTCTCGTCCAACTCTTCAAACCAATCCGATCATTCTCTGCCTACAAAGATTGCAAAGTTGGAAGCTCGTATGGTTGGTAAGGGTTCCTCAACCTCTTCTCAGCAACCAGGTTGGTCCTCTGTGTCTGTTCCTTCGGCTGGGAAATTTGTTCGAGCTGTTGAAAATTCGGCTGAAGCATCCACTTCAAGTGATTCTGATGATGATGTAAGTTTAATCCTTATTCAGTGCGTGGGTTTGGTACTTTGACTGCACTTGGGAGAACTATTACTTTTAGGTTTTGGCTTTGTTCTTTTGTTGCTCGGGATTTTCAATGTTAATTTTTGATTTTCAATGTTAATTTTTGATTTTCAATGTTAATTTTTGTAGCTTCTTTTTGTTTATTTTGGTGGTTTATTGCTTGAGTATTTATCTATGGTTTAGGATATAATGTATGTAGGCGGTATGTTTTGTGTTCGTTGCCGCCATTTCTATGTTGATGATTTAGTAATCTGGATAACTGGTAGATGTAAGGAAACATTTTTCTATGATAACTTCAATGATTAGATTATTGGTATCTTTGTATTTCTGTTCCAGAATGGTGGGGCATTCTTGATACAAGCCAACACATCGAAGCGACAAAAACTTCAAGAAGATGGCAACACTAGTGTTTTTGAAAGCGTTGAGGTTGGTTTTTATGATCTTTGATTTTATACAATAACTGCATCTGTTGTTGAAAATACAGCTATTTAAATTGCATCCTTTATAAATATATTGTTCTCATCACCTTCGGTATCTAGTATTTTGATGACTTTAACAGCCACGTGTAAAATGTGTACATTTTGTCTTAGAAACTGGTCATCTAGTGATTTCTAATCCAACAGAAAATAATTTACATATTAGGTTGTTACTGATGGAAGGCAAACTAGTTTGGATGCCGTGGAGACAAAAATGCACATTGAAATGAATAGAAAGAAACATGGTCGTGGAAGAGGGAGTTCTGGTTCGGGTAGAGGCCGGGGTTCCAGAGTTAATGATCAGATCAAAACACTAATTTCTTCTCCAACTGCTTTGACTTCAAATGGTCAGATCGACAATGTATACCATAAAGTATGCTCATTGCCATGAAATATTTGTTTCTTTAATTCTAATTTTTAAATTGTCCCTATTGGTTTTATCTAAACTGGTCTTATTAATTATGATCCTATCTGTTGTCTATACATGATTGGAAGCATAGTTGCACACCCGTCTCTTCTTTAATTGATATTATGTAGTTCTGAGGTTTAAACTTCTTGGCTTGAAGGATTACTGCAGGAAGGATTGATTGTATCATCTATAGTCTGTAGCTGAAAGGAAATTTGATTGCATTGGTTTTGGGTGCCCTTTTTTGTTTCTTGTTTTTTTCAATGGTTACCAAGTATCAGTGTAATGTCCTATAAAGCACTCTGTTTTCTGTAATCTGCAATGCTTATTTGATATTGTTGTCTGGTTGCGTCTTCTTACCTGTTATGCAAATTGGAATCTTTTCTGATTCCTACGAATGGAAGGTTCATAAGTTTAGGAATGTCATATTGCTTAAGCAATTAATTTACATGTTAATAAGTTATTTTTCACTCCTTGGTTGTACCCTATAGAGCTTATATTTATTTGCAGGGTGGCAAACCCAGTGATCAGTTTCATAGTGATAATTGTATTTCATTAGAGGTATGACTTTTTTCCTAATTCCACTTGTAAAATGTGTGGCTTTATATGAAAACAAATAGAAGTTTGGTATGACTTCTTTCATTTCTACCTCCTTCCACCATATCCATGACATTGATGATGCTTTAACTCTTCATTGTTGTTTTATTAAGGTAGCATAAGCTTGTAATTTTCAAACTTTTTCTCATTTTATTTCATCGATATCTTAAATTAGGACGAGGTTGCATCTTTGCAAGCTAAAATTGTTGCTTTGGAGGAGGAACTGCGGAAATCAAAGCAAGAAGCAGTCGATTATCAGAATCTTACTCAGCAACTAGAAAAGGTATATGAATGCCACAGGCTTATCACAATCAGAAGAATGTTTTACAAATCTTTAATTGTATCGAGTCTTGTGTGTGTGTGTTTTTTTTTTTGGGGGTGGGGGGGGGGGGGGGGAGGGGGTTATAAACACAATGCCTCCAATAAGCTTACTGTTGTGCCGAGGTTTCCCTCCCAAATTTAAGTATGTCAATACGTATATGGCACTTAATTTGTTGTCAAAATCAATCATATGTCTTACATAAATCTCAGATTCAAAGATAAAGTCCAGACTTGAGTATAAAAAATTGATTCATGATACATTTCCACTAGAAGGTAAAGCTGGGCAATTGCTATTATGGCATCTTTCTACTTTATTTATTGTTCTTTGAAAAATAGTTGTTTTGACTTGAAATTAGTGTGTATTTTTTTGTTTGGTCATGCAGATTTGAACTTCTTTATTGCAATCTCACAGCCAAACCAAATCACACTTAAATCTTCTGTTCAATTGCATTTTATAATAGTACCATAATAGCTGAGACAGTTTTTTTCATATACACGTTTTTTAAGAAGGTACACAGTTTGCAATTTTCTTATCTTTTGCTATTTTGGCCACACAGATCTAAACCGGGGCTGTTGTGGTCTGAAAAATACTAGATGCTAGTGAAAAGGACCAAATCGTGTGATTCTATTTGCAATATGCATGATTTTTATACCATTGACTAATACTCCCAATTTTACGAACAAAATAACAAGGAATATATACTGAATTGCAAAAATATATTTTAATCTTAAGAGAATTGAGAATTATTGAAGTTGATGTGCTGATTTTCTGTTCTTATAGTGTTATTGCTTGATTTTGGCACATGCAGGAAATGAAGGAGATGACTGATCATGAACAACAAATGAAGCCTAAGGTGTGATATTTTCAGCTTTGATTGCAATGAAAGCTTTCTTCTTGAGTCTATCAAAACACTTCATCACTAATTATGTACCTTTATTTGAATAATGAGCACTGGCTGTCTTTACAGTACATGAAACTGAGTGCAGACACTAAATCTTGTCTGCTTGAATTCTTTATGCAAAAGTGAGCTAGAAATCTTGGACAGCTCATTGTTGATACACAATAAATGGGGCGATGCCAGGATCTGGCTTCTCTAAAAGCTATTTACTTTAGCAAGGATAATAAGCATTAAGTAATATGAATCATTGATGAGAAAATCAAGAGTTGATATTAAGTGCACATGTGTAGTAAATCATGCATGTGTTGGAATATTAAACAATTATTTTCTCAATGAGTAAGATTACTTTCTTAACGTTTACTCACTTTCCTGGAGTTAATCCCCATCACCTCCTCCCCCGCCCCCTTCCCAACAAAATAGTTAATTAGCATTCTTTGTATCATGCATCAATTAGGCAGCATATTCACATTTGATCTTTCTATTTTGCAGAGGATGAAAGTAATATCTGACTTGCTGATATCCGTTTCAAAAGCCGAAAGACAAGAAGCAAGACTAAAAGTACGACAAGACTCATTGAGACTTGGAAATGTTGGTGTAATCAGGTAGGCATGGAGCATTTTAAGAAATTACATAATTATCGATCCCGAATAACAGTGTGGAGCTGCTGACACCAAAACTGCTACAGTGGGGTAGTTGCTATTGTGAAAATTTAAAAATACAAGTTAATAATTTATACATATACATATATTTAACCAAAACTAGAGGCATTCATATTCTGGCAACAGAAATGAAACTGGGAAATTTTATTTCATATTATATCTTTTTTACTAAGTTTCTTATTAGTTAAATAATGAATTGTAGAGCTGGAACTGTCATATCTGAAACCTGGGAAGATGGTCAAGCTTTAAAGGATCTGAATGCCCAGCTTGTATGTCCCATTTCCTTTCTCTTTCTTCATGACTTTTCTTTTTAATTTTTGTACTGGAGATTGTTACTGATTGTGATTAGTTTATCAGATTCAACTAGGATTTGTTGTGAGATTTGCTGATTTAGGAATCATTATAACACATTTTTTAGGATTCTGGTTCTTTCCTACTTGTCTGTGATCAATATCTTTCAATTTGATTGTTTCTGATTGAACGTTTCATATTGTCATTGTCTGAAGACCCACTGATGTTCAATTGTGCAGTGAAATTACATAGTTTTCGAAAACCCTAGATTATAAATACTACAAAACCTGAACTCTTTTGCTTCACTTTAGTGAATAAAATTATAGGATAGTGTTTTGAAATGTTAAGTGTTTTTCTTCTCAGTATCTTTTGGCTATAACACTGGGTGTATACTGTTAATTTCACCTCAACTTCTATTTGTTATTTTTCTTTTGCAATTTAAATCTTGCCTATGTTGATAGTTACATTAGTGATACCAAGAATACTTTCTCCTTCTTATTCTTTGTTTTTTCCCCAGAAACAACTAGTAGAAACCAAGGAGGCAATAGAACGACAGCGCAAATTGTTTAAGAAAAAGCAATCTGGTAAATTCTGTTTCATTTTCTCTTTCGGCACCTATCCTTGTAATATTGGGATAGAGTTTGATGGGACCAAATTTGGGACAGTTGTTATGACTTCCTCGTCCCATTCTTAGTTTATACCAGCCATTGGTATGAACATTCCATGCATGTTGTTAAATCTCTACGTTAGGTACTTTGTATATATTGAATTTCAATAACTTCGCTAGATATTATACAAATCATGATAAACCATATGCTCCTTAAGGATGTTGATAGGAACTTGGGTATTATGGGTGCCTAAGTCCCTCATTGAGTAGTATGGGATGTCTGGTGATGTATTTAAGTGTTTTGTTTACCTCCTTGATAGCTAGCCTTTGAGGGTGGGTTCCCCAAGTGATTGGTGTAAAGCGGGTTGCCTGTGTCTTAGGGGCAGTGCTATAGTAGGAACTTGAATATTATAGAGTTCCTAAGTCTCAAAGTAGAATGGAATACTCCGTGGAATATTTAAGTAATTGGTTCTTGCCCCTTAATCGAAAGGTTTTGAGGGTGGATTGCCTGAGTGCTGGTGTTGGAAACCCAAAGAATAGTTATAGTAGAAAGAACAATTCACACATAAAGGAATAAACCCCAGTATTATTGAATGACAAACTGTTAGGAATCCGAGAATAGGATCCTAACCGTGTAAGACGAGGACCTAACCCCTTTCACGAGGTGTTGAAACCGGTCTATACAAAGTATATGATTTTTCTCTCTCTAATCACAGTATAATGTGTTATTCCTTATATACCTATACTTCCCGCCTTTTTTCTCACCGCCTCACCGCTAAGGCAGTTAGGCCTTCTTTTTCTTCCTTCTTTTATAAACTATCCAACTCCTAACACAAACGAAAGGAAAATACAAAAATCAGATTCTGTCCACAGAGCCTAGCTCCAACCGAGAGCTATTGTTCCCTGCCCATAAACTTCCAATACCCAATGATACCCACTCTCGTGCCAGCTCATCATTCTCTCACCCTCCTATTCATCCACTCATACACTCTCCAAATAATGGGCTTGGGCCTACTATCCAATTGCCTGCTTGGGCTGCTGTCAGCTGGGGTACCTATCTGTTATTCAAATGGACAGTTTGATATAAAAAGTATCTGTCACACAGTCACAAATCTCTCGACTATATGTTGTACTATATTACTCTGTTCCCTGTGTTAATAGTGTGTTTTGTTGTTGTCCTTCTCTGTTGAAGATAAGGGTGATGGGACAGATGCAGAGGCTGGATTGCCAGAAGATATTCTAATTCACGATGAAATTTACAAGTGTCGATTAGCTAGTCTTAAAAGAGTAAGTTGCTATTTCTGCTGGTCCAACTGTTTTCTTTCTTCTTTATGTTTCTAATAGCATGAAAATGTTCAGGAAGAGGAGATTGTTTTACGAGAGAGGGATCGGTATGAAATAGAGAAGGGGAGGTTAATTCGTGAGATGAAACGCATACGGGATGAAGATGGTTCACGGTTTAACAACTTTCAGATTTTAAATCATCGTTATGCTCTTCTTAACCTTCTTGGGAAGGGAGGATTCAGTGAGGTGTACAAGGTCAGATCAGAAATAATAATCATTTGATCATATTGATATTGTTTTATCTGGAAAAATGCTAGCAAGACACTCTCTAAACACACTTTTATAAACTATTTATCATTGGCAAAATGATTAGATATCGCATTCTGTATCGACATTAACATTTCCACTAATGATTTTGTACTTTTCAATAAATTTTAACTCACAAAGTGTGTTGCTATTCTACTCATTTGGGAAATATTATACACGGCTTTCAAAAACTAAGACCAGTGTCTGGATAGTTACATGGCCTACTTTGGCAGTTGTAAATAAATACCTTTTTGCAGTGATTTGAAGTAAGAAATTTCCAGCAGGCTTTCGATTTGGTGGACCATAGATATGTTGCTTGCAAACTTCATGGTTTAAATGCTCAATGGAGTGAAGAGAAGAAGCAGAGCTACATACGACATGCAATTCGGGAGTATAATATTCACAAGACTCTTGTACATCGTCACATTGTTCGTTTATGGGACATCTTTGAGATTGATCAGAACACGTTCTGCACTGTTCTAGAGTATTGTAGTGGTATATTATTTTATGAAGTTTATTATTTTTATTAATTTTACAGGCTCCAAATATTTCTTTGGAGCTTGAACCCGAATAAATTTGCTGTCTTTGTTTGATTTATTGTTTAATCTACCCTTTGCCCTTGACTTTCCTTAATTCTTCCAGGGAAAGATCTTGATGCTGTTCTTAAAGCAACGCCTATATTATCTGAGAGGGAGGCTAAGGTCATCATAGTTCAGATTTTTCAAGGTCTTATTTATATGAATAAAAGAACACAGAAAATTATCCATTATGATTTGAAGCCTGGAAATGTTCTGTTTGATGAACTTGGTGTTGCCAAAGTGACTGATTTTGGTCTTAGTAAGATAGTGGAGGATGATGTTGGATCCCAAGGTATGGAACTTACGTCCCAGGGAGCTGGAACATATTGGTAAGTGGTGGCAATCTTCGTTGGAATTCAAAATGTGAAGTATTTCAAATTTGTAGGTTTTAGGCTTTACTCTCCTCAATCTGGCTTAAACTTTGACACTCCTTTTTATGTTTACTTTAGATTCCAGTATTTTACTTTGGTAAAACCTCTTTATCCGCTCTTTTTCTTTTTTCAATTTGTAGGTATTTGCCTCCTGAATGCTTTGAGCTCAGCAAGACACCTCTTATATCATCAAAGGTCAATGACTTTCTAAGTTGTGAATACACAGATAATTCTTATTTTATATGCAAACAACCAACCCTTTGATCATCACGTTAAATATTTTTATCATTTGGCTCATATATTTTCCGACATGTTATGGAAGACAGGTTGATGTCTGGTCTGCTGGTATTTTGTATTATCAAATGCTCTTTGGCCGACGACCTTTCGGGCATCACCAAACCCAAGAGAGAATACTTCGTGAGGACACAATTATTAAGGCTCGGAAGGTTGACTTTCCTTCTAAACCTACCATTTCTAACGAGGCAAAGGTGAGTTGCACCCTTTTACTGATAATTTCTGTACATAGTTGATGGCTCTTTTTGCCTTGCGTAATTTTTTTTATTAAGGGTATTTTTCAAAATGAATGCCATGCACTTAGGTGCATTAAAAATTGCAGTAGAATTGTATCATCATACTTCTTAACAAAACTTCTGTTTTAACTTCATAGCTTGCGCATTTTCCTTCCTTTTGTTCTATTATTCAGTGATGGACTATGCTTCTTCTAAGGTTGTATGTGTGTTATGTTCATTTTCACATAACCAAAGATTCAAACATATCCCACATGCAAGTGTAGGAACTAGGAAGTTTGTGGTTTCCTTTGAAGACCTCAATGCATACACTTTCTTATATCCGGTTTGCTGTAGAAATATTATAGTATCATGTACCTACTATCTACAATACTGTCAAACCTGACAATAGTCTGTGCTGTATGTACATCTTTTCTGTCAGGATTTTATCCGAAGGTGTCTAACATATAACCAGGCTGAGAGACCAGATGTGTTAACCATTGCTCAAGACCCATATCTCACTTTCTCAAAGAAGTAAATGGCATTCATTATTCAGACTCCCCAAAGTCGAAGGATCTCATCTTCTAATGTCAGTTACTGGTTCTGTTAAATTTTGTATACGTTGTAAAGATTTTGTAACCTTATCAAATGAGGCAGAGAAGGGGTTTTCCCCGGTCTGAAAGAAAGTTGTATTTGTTTTCATACATCATCTTTTGGTTTAAGATATGGGGTCACCAAATGGTATGTGTATTTGTTTTTGACCTTCAAACGGGTCAGGAAGTATACAAGAAAATGATAAAGCTTTTTGTTATTTTTTGAC