Gene Details:

Gene ID Chr. No. Start Position End Position Function View on
Vu_05684 LG1 84912199 84924317 PREDICTED: phototropin-2
Map

Annotations  
category   relationship type   keyword
Biological Process   involved in   protein phosphorylation, negative regulation of anion channel activity by blue light, protein autophosphorylation, phototropism, stomatal movement, protein autophosphorylation, protein phosphorylation, stomatal movement, negative regulation of anion channel activity by blue light, protein phosphorylation, protein autophosphorylation, chloroplast relocation, phototropism, negative regulation of anion channel activity by blue light, response to blue light, circadian rhythm, protein phosphorylation, protein phosphorylation, phototropism, protein phosphorylation, phototropism, protein phosphorylation, protein phosphorylation, chloroplast relocation, protein phosphorylation
Cellular Component   is active in   cytoplasm, nucleus, plasma membrane
Cellular Component   located in   plasma membrane, plasma membrane, nucleus, plastid, plasma membrane, plasma membrane, Golgi apparatus, membrane
Molecular Function   enables   identical protein binding, protein kinase activity, identical protein binding, protein serine/threonine kinase activity, protein kinase activity, blue light photoreceptor activity, FMN binding, FMN binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity, protein binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, FMN binding, protein kinase activity, protein serine/threonine kinase activity, protein kinase activity, FMN binding, protein serine/threonine kinase activity, kinase activity, protein serine/threonine kinase activity, protein kinase activity
Pathway   B 09181 Protein families: metabolism   C 01001 Protein kinases [BR:ko01001]
SNP Position Effect Amino acid change
C/G 84912407 splice_region_variant&intron_variant
C/A 84912570 intron_variant
A/T 84912678 5_prime_UTR_variant
A/G 84912897 missense_variant p.Asn64Ser
G/T 84913003 missense_variant p.Leu99Phe
A/T 84913078 synonymous_variant p.Ala124Ala
G/T 84913093 synonymous_variant p.Val129Val
C/T 84913108 synonymous_variant p.Asn134Asn
T/A 84913211 missense_variant p.Ser169Thr
C/G 84913212 stop_gained p.Ser169*
T/A 84913515 intron_variant
A/G 84913684 synonymous_variant p.Pro265Pro
A/G 84913970 intron_variant
G/T 84913996 intron_variant
G/T 84914035 intron_variant
G/T 84914431 intron_variant
T/A 84914435 intron_variant
T/A 84914795 intron_variant
C/A 84914796 intron_variant
T/C 84915342 intron_variant
T/A 84915347 splice_region_variant&intron_variant
C/T 84915563 stop_gained p.Arg388*
G/T 84916197 missense_variant p.Arg501Leu
T/C 84916230 intron_variant
T/A 84916306 intron_variant
T/A 84916311 intron_variant
A/G 84916355 intron_variant
G/A 84916365 intron_variant
C/G 84916394 intron_variant
T/C 84916434 intron_variant
C/T 84916502 intron_variant
T/A 84916776 missense_variant p.Ile534Asn
T/A 84916792 missense_variant&splice_region_variant p.Ser539Arg
T/A 84916795 splice_donor_variant&intron_variant
T/A 84916799 splice_region_variant&intron_variant
T/A 84916803 intron_variant
T/A 84916839 intron_variant
A/G 84916848 intron_variant
G/A 84916851 intron_variant
C/A 84916881 intron_variant
G/A 84916937 intron_variant
T/A 84916946 intron_variant
T/A 84916960 intron_variant
C/A 84916966 intron_variant
C/T 84916986 intron_variant
C/T 84917101 intron_variant
T/A 84917201 splice_region_variant&intron_variant
A/G 84917202 splice_acceptor_variant&intron_variant
G/T 84917226 missense_variant p.Gly564Val
C/T 84917227 synonymous_variant p.Gly564Gly
A/T 84917263 missense_variant p.Leu576Phe
A/G 84917410 intron_variant
G/C 84917442 intron_variant
C/T 84917523 intron_variant
T/A 84917588 intron_variant
T/C 84917633 intron_variant
G/C 84917703 intron_variant
A/G 84917730 intron_variant
A/G 84917787 intron_variant
G/A 84918281 intron_variant
T/A 84918304 intron_variant
A/G 84918306 intron_variant
G/C 84918565 intron_variant
C/A 84918813 intron_variant
T/A 84919195 intron_variant
C/G 84919204 intron_variant
A/C 84919488 intron_variant
T/C 84919535 intron_variant
T/A 84919790 intron_variant
A/T 84919794 intron_variant
G/A 84920494 intron_variant
A/G 84920593 intron_variant
G/T 84920701 intron_variant
C/A 84920705 intron_variant
C/A 84921474 intron_variant
G/A 84921606 intron_variant
A/T 84921613 intron_variant
T/C 84921661 splice_region_variant&intron_variant
A/C 84921779 intron_variant
T/A 84921818 intron_variant
A/T 84921819 intron_variant
T/A 84921827 intron_variant
T/A 84921841 intron_variant
T/A 84921900 intron_variant
T/A 84922469 missense_variant p.Trp865Arg
T/C 84922565 intron_variant
G/A 84922624 intron_variant
C/T 84922668 intron_variant
C/T 84922695 intron_variant
T/C 84922724 intron_variant
A/G 84922727 intron_variant
G/A 84922728 intron_variant
G/C 84922738 intron_variant
C/T 84922748 intron_variant
A/T 84922768 intron_variant
T/A 84922772 intron_variant
C/G 84922778 intron_variant
T/C 84922782 intron_variant
T/A 84922786 intron_variant
T/C 84922801 intron_variant
T/G,* 84922966 intron_variant
T/G 84922967 intron_variant
T/C 84923085 missense_variant p.Ser891Pro
G/C 84923263 intron_variant
T/A 84923436 splice_region_variant&intron_variant
G/A 84923454 synonymous_variant p.Ala909Ala
C/T 84923550 synonymous_variant p.Phe941Phe
A/T 84923643 intron_variant
C/T 84923774 intron_variant
A/G 84923981 synonymous_variant p.Leu957Leu
G/A 84924125 3_prime_UTR_variant
T/C 84924186 3_prime_UTR_variant
C/A 84924304 3_prime_UTR_variant
T/A 84924315 splice_region_variant

View accession wise SNPs


Sequence Details:

Protein Sequence:
>Vu_05684.1
MEKLKVSTKHDSDGSSDQADSFPIFELRESQNVGQQRYRREEDDTKAVRFDGASAIASSNSASNKESANKWMAFARDPGSAVDSNSAVNDKSTTEDNYLRNHLSDKSSSDQQVLTEATIAERTAEWGLVVNSGNFKTSSSFDGDRTRNLSDRFVESTRTSGDSNFGSESSSGVLRVSQELKDALATLQQTFVVSDATKPDCPIMYASSGFFTMTGYSSKEIIGRNCRFLQGADTDKNEVAKIRDAIRNGRSYCGRLLNYKKNGTPFWNLLTVTPIKDNQGNTIKFIGMQVEVSKYTEGVNEKALRPNGLPKSLIRYDARQKEKALGSITEVVQTVKDPKSIIKNRSDDNASMQEVEQKMNLDFALPKSAVAGNTSTPGRQPSPLNIQRVSSNQEKVRTSRSGRISFKGFKGKSQSYSGRDEEKYTVEPEILMTKEIEWSNNLENSLRERDMRQGIDLATTLERIEKNFVISDPRLPDNPIIFASDSFLELTEYTREEILGRNCRFLQGPETDQATVSRIRDAIREQREITVQLINYTKSGKKFWNLFHLQPMRDQKGELQYFIGVQLDGSDHVEPLKNRLSETTELQSAKLVKATAENVDEAVRELPDANLRPEDLWAIHSQPVYPRPHRKDNPSWIAIQKVTARGEKISLKHFVPIRPLGCGDTGSVHLVELKGTGELYAMKAMEKSVMLNRNKVHRSCIEREIISLLDHPFLPTLYTSFQTSTHVCLISDFCHGGELFALLDKQPMKIFKEESARFYAAEVVIGLEYLHFLGIIYRDLKPENILLQKDGHVVLTDFDLSSMTSCKPQVVKQALPGKRRKSRSEPPPILVAEPITQSNSFVGTEEYIAPEIITGAGHTSAIDWWTLGILLYEMLYGRTPFRGKNRQRTFSNILHKDLTFPSSIPASLAARQLINALLQRDPTSRLGSTTGANEIKQHPFFRGINWPLIRNMSPPPLDVPLKLIGKDPVAKDINWEDDGVLVSSIDMDIF*


CDS Sequence:
>Vu_05684.1
ATGGAGAAACTCAAAGTGTCCACAAAGCATGATTCTGATGGCAGCAGTGATCAGGCAGATTCATTTCCAATATTCGAATTGCGCGAGAGTCAAAATGTTGGACAGCAGAGGTATAGAAGAGAGGAAGATGATACAAAAGCTGTGAGATTCGATGGAGCTTCTGCAATTGCTTCCTCTAATTCTGCAAGCAATAAGGAATCTGCCAACAAGTGGATGGCATTTGCTAGGGACCCTGGTTCTGCAGTTGATAGCAACTCAGCAGTAAATGATAAAAGTACCACTGAAGACAATTACTTGAGGAATCATCTGAGTGACAAGTCTTCTTCTGATCAACAAGTTTTAACTGAAGCAACCATAGCTGAGAGAACTGCAGAATGGGGTCTTGTGGTGAACTCTGGGAACTTCAAAACCAGTTCTTCTTTCGATGGTGACAGAACCAGAAACTTGTCAGATAGATTTGTTGAATCAACAAGGACATCTGGGGATTCAAATTTTGGATCTGAGTCATCATCAGGGGTTTTAAGGGTGTCACAAGAGTTGAAGGATGCATTGGCGACGCTGCAACAGACATTTGTTGTCTCAGATGCAACTAAACCAGACTGCCCAATTATGTATGCCAGTAGTGGCTTTTTCACTATGACTGGCTATTCTTCAAAGGAGATTATTGGAAGGAATTGTCGGTTTCTTCAGGGGGCTGATACAGACAAGAATGAAGTGGCCAAAATTCGGGATGCTATTAGAAACGGAAGAAGTTATTGTGGCAGATTATTAAACTACAAGAAAAATGGAACTCCATTCTGGAATCTTCTCACTGTCACCCCAATCAAAGATAACCAAGGCAATACTATCAAATTCATCGGAATGCAGGTTGAGGTGAGCAAGTACACTGAAGGAGTGAATGAAAAGGCGTTACGACCAAATGGATTACCAAAGTCATTAATTCGATATGATGCTCGTCAAAAGGAAAAAGCTTTGGGTTCCATCACCGAGGTTGTCCAAACTGTTAAGGACCCAAAATCTATTATTAAAAATAGGAGTGATGATAATGCCTCCATGCAAGAAGTGGAACAGAAAATGAATCTTGATTTTGCTTTGCCAAAGTCTGCTGTTGCTGGGAATACAAGCACACCTGGTAGACAACCTTCTCCACTTAACATCCAACGAGTGAGTTCTAATCAGGAAAAGGTCAGAACATCACGATCAGGACGGATTTCTTTCAAGGGTTTTAAAGGGAAATCTCAGAGTTATAGTGGGAGAGATGAGGAGAAGTACACTGTTGAACCTGAGATTTTGATGACCAAAGAAATAGAGTGGTCGAACAATTTGGAGAACTCACTAAGAGAGAGAGACATGAGGCAAGGAATTGATCTAGCAACCACATTGGAGCGGATAGAAAAGAACTTCGTGATTTCTGATCCTAGACTGCCAGATAACCCAATTATATTTGCATCTGATAGCTTTCTTGAGCTTACGGAATACACACGAGAAGAAATTCTGGGACGAAATTGTCGGTTTCTTCAAGGACCAGAAACAGATCAGGCAACTGTTTCCAGGATAAGGGATGCTATCAGAGAACAGAGGGAAATCACTGTTCAGTTGATCAACTATACTAAGAGTGGAAAGAAGTTTTGGAATTTGTTTCACTTGCAACCCATGCGTGACCAAAAGGGTGAACTTCAATACTTCATTGGCGTTCAACTAGATGGAAGTGATCATGTAGAACCCTTAAAAAACCGCCTGTCTGAGACAACTGAGCTACAGAGTGCTAAGTTGGTGAAAGCCACTGCAGAAAATGTGGATGAAGCTGTCCGAGAACTTCCCGATGCCAACTTGAGGCCAGAAGATTTGTGGGCAATTCATTCCCAACCTGTATATCCACGACCTCACAGAAAGGATAATCCTTCTTGGATAGCAATACAAAAGGTTACTGCAAGAGGCGAAAAAATTAGTCTGAAACATTTTGTGCCCATAAGGCCACTAGGTTGTGGAGATACTGGCAGTGTTCATTTGGTGGAACTCAAAGGCACTGGTGAACTATATGCAATGAAAGCAATGGAAAAGTCTGTCATGCTAAATCGTAATAAGGTTCACCGATCATGCATTGAGAGAGAGATTATATCATTATTGGATCACCCTTTTCTTCCAACACTATACACCTCATTTCAGACTTCTACACATGTATGTTTGATTTCTGACTTCTGCCACGGGGGAGAATTGTTTGCATTGCTTGACAAACAACCAATGAAGATTTTCAAAGAAGAATCAGCAAGATTCTATGCGGCAGAGGTTGTCATTGGTTTGGAATATCTCCACTTTCTAGGTATAATTTATCGTGACTTAAAGCCTGAAAATATCTTACTTCAGAAGGATGGTCATGTTGTATTAACTGATTTTGATCTATCATCTATGACATCGTGTAAACCCCAGGTTGTGAAGCAAGCATTACCTGGTAAAAGAAGAAAATCACGAAGTGAACCTCCACCAATACTTGTTGCAGAGCCAATTACACAATCAAACTCATTTGTTGGAACTGAAGAATATATTGCCCCTGAAATTATAACTGGAGCTGGGCATACCAGCGCTATAGATTGGTGGACTCTTGGTATCTTATTGTATGAGATGCTGTATGGTCGCACACCATTTAGAGGAAAGAATAGACAGAGGACATTTTCCAACATCTTACACAAGGATCTTACCTTCCCAAGCAGCATCCCGGCCAGTCTTGCGGCCAGGCAGTTGATTAATGCATTACTGCAGAGAGATCCAACAAGTCGTCTAGGTTCAACCACTGGTGCAAATGAAATCAAACAACACCCTTTTTTCCGTGGAATCAATTGGCCTCTAATCCGCAACATGAGTCCACCTCCATTAGATGTTCCTCTAAAATTGATAGGAAAGGATCCAGTGGCGAAGGATATAAATTGGGAAGATGATGGAGTGCTAGTTAGCTCCATTGATATGGATATTTTTTGA


Promoter Sequence:
>Vu_05684::LG1:84910199-84912199(+)
GGTAATTGATTATTACAATGAGAAAATGTTTTTGGAAAAGCTTATGTGATAATCATTTATCTCTTGAAATAATCGATTATTAGCAACAATTTTGACTTGACTCTTCAGGTTCTTGACCTAATTTTCAAAAGAGAAAGTTTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGTGGGTGTGTGTGTGGTTAAACCTAATTTTGAATGCAACTTTTCATTAGAGGTTTAGGGATATGATGCTAGAAAAACTCTGTATTTGTCAAAAGGGGTTTTGAAAAATCAAGAGCGGTATAACTAATCTCAACTTGAGCTAATGATGAATGAATATTCTCTTATTAAGAATCTAGATGGTGGTGTGGTAGTGGAATATCATTTAGCGGAGGAATTGAAAATAGTTTTCAAATGGGATAATATGCTTGATGAGAGAAAAAATTCTAATACTAAATGAGTCAATTCAAGCTAAAAAAACTTGATAGGAGAAGGTAAAATAAAGTTAATATTAAATCTCCAAAGAAAAACTTATAAAATTTAAAAGTATTTTTTGGAATACGAAAGGATTGATTAATGATAAAATTTTTAATATACTTAAGAATTTTTCTTCTTTTAGGTATTTGGAGTTCAAAATAATGAATGACTTTTGTGAAGAAAATAATGATTTTTCTTTTTTTGTTCATGGTAAATATTCTTTGACTATATTCGTGAGATGTAATCTTATCGTGAGTTTATTGTGGTCCTCATTTTTTTTCTTTCTTTTTTATTTTTTAATAAGTTCTTTATGTAATGAATTGCATGTGCTTATCTAGAATAACTTAAAGAAATTTAAATTGAAATTTAAGTTTATAATAAATTATAAACTATTGAGTTGTAAATTTAAGTTCATGTTTTTATTGAAAAAGAGTTAAGAATATAATAATTAAATTCTTTCAATTATTACAATTATAAAAGTTTTTTAATTTATTATTAAATTTATTTTAAGTTTACAGAAATTATATATTTTTATATACTGAAATAGAATATTTAATTATTTGCGTTCATAATATACAAATATATATATTTAAATTCTTTATTTTAATTAATTATATAAATAATTTAGATACAGTTTTACAATAAAAATATCATGATTTCAATTTACAAAATAAAATAATTATATTTTTTATAAACTTAAATTCATATTACAAATATATATATATATATATATATATATATATATATATATATATATATATTTTAAATCCATTAAATAGAAACAATAAGTTTTGATCATGGTACATCAGAAAAAACTTAGACCGAATCGAAGACAACTGAGTAGATACAGTGTTACATTACCTTGTGTCCCGAATGTTGTCTGTCAATTGTTGTCTAAATGTGTTTGTGTTTTAAGGCGAAGGTTAATCACTCCCACGTGCTATCTGTATCACACGATAATGCGCCTATGCATGGCTGACAGAGTTACTCAGCGTTGTTGCGTCTGCTGTCGTGGAAGTTTCTACCACCACATCGCAATGCCACATATCACCTTCCCCTCTATTATTCTCACTTGTCATCTTTCTAAAGGGAACCCAAATATTAAATTTTGATAGTGAAATTTATCTCCAATAATGTGCCACGCCAAATACGTTCTGGCCTCACAATTTTTCCTGACCCCACCTCGCCTTTTCATTATTTTTACCACTTCAGCGATCATCACAACTTTTACCACTTCAAGGATGCATCTCATTTATCCTTAACTCTGTAAAACAAATATAAATTGTTGTCTGAATCTTACATGTCAGATTGATGATTAAATGTTACAGTTTTATCTTGTTGTGCTCTTTTTTTATACAGAGAGAAGGACTGATATCTATTTACGGTTACTGGAGATTCAAGGGAAAACCACTGAACATGAAGAAAGTAGAATCCGATGAAGTCTACGTCAATAGTAGTGAATTTCAAACGTTAAAAGATGTGATATTCCAGCTTTTGTTTTTA


Gene Sequence:
>Vu_05684(+)
ACTTATTTCCAACCTAGAAGGTGGACAAAATAAATGGTGTATGAAATGGATATTACACATTTGCTGTTGCCTCAAGAATATTTTGTTTTTTTAAAGAGAAATATTTAGCAAGTGTTGGGCGTGTTTATGTGAACCTCCAACGTTATCTTTTCTATTTGAGGTCCAACATGAAGTGAAAGCGGAAAGACATTTGAGAGAAAGGTTAATTCTCCAACCGAATCACAAGACCATTTTCATGTTTTCATTACAAACTTTTCACGTTTCGATGTTTCTTTCCTAAAGAGACTGTGTGTGGTTATTTTTACCAGAGGAAACTCTGTCCCTCTCTCTCTTTCTGCACAATTTGGTGAATTTTGGCTAGCTTTGTTGTTCTTTTTCTGTGTGTTATTTATTGCATGTACGTTATGTACTTACACTCATTAATTCTTTCTCATTCCAACAGAACCTTAGGTGGTGGTGGTGGTACTTGTTCTGTAGTAATCATCAACAGAGATAAGATAACTCATAAATGGAGAAACTCAAAGTGTCCACAAAGCATGATTCTGATGGCAGCAGTGATCAGGCAGATTCATTTCCAATATTCGAATTGCGCGAGAGTCAAAATGTTGGACAGCAGAGGTATAGAAGAGAGGAAGATGATACAAAAGCTGTGAGATTCGATGGAGCTTCTGCAATTGCTTCCTCTAATTCTGCAAGCAATAAGGAATCTGCCAACAAGTGGATGGCATTTGCTAGGGACCCTGGTTCTGCAGTTGATAGCAACTCAGCAGTAAATGATAAAAGTACCACTGAAGACAATTACTTGAGGAATCATCTGAGTGACAAGTCTTCTTCTGATCAACAAGTTTTAACTGAAGCAACCATAGCTGAGAGAACTGCAGAATGGGGTCTTGTGGTGAACTCTGGGAACTTCAAAACCAGTTCTTCTTTCGATGGTGACAGAACCAGAAACTTGTCAGATAGATTTGTTGAATCAACAAGGACATCTGGGGATTCAAATTTTGGATCTGAGTCATCATCAGGGGTTTTAAGGGTGTCACAAGAGTTGAAGGATGCATTGGCGACGCTGCAACAGACATTTGTTGTCTCAGATGCAACTAAACCAGACTGCCCAATTATGTATGCCAGTAGTGGCTTTTTCACTATGACTGGCTATTCTTCAAAGGAGATTATTGGAAGGAATTGGTGAGCATTCCTGTCTTTACAGTAGCAATATATGTTGTTTCAATCACCCTTATAGATAGCTATTTTCACCAAAAGTAGCTAACTGAGGAAAACATACTCTGCACATGGGAAATTTATGCCAATTTAAGATGTTTAACTAAAGAATGCATAGTTATTAATGAAGCATCCAATTTCTGGTTTCAGTCGGTTTCTTCAGGGGGCTGATACAGACAAGAATGAAGTGGCCAAAATTCGGGATGCTATTAGAAACGGAAGAAGTTATTGTGGCAGATTATTAAACTACAAGAAAAATGGAACTCCATTCTGGAATCTTCTCACTGTCACCCCAATCAAAGATAACCAAGGCAATACTATCAAATTCATCGGGTCAGTTCTGCCTTTCCTATTTGGTTTTTCCTGGTTTTCATGACCAACTTGTGTATTACTTGTATCATTTCTACTGAAGCTCACTTGTTATGTAAATGTGAACACTTTCTGTAGATTTACAGAAGTAGCTCTTTAGGTTGATTCTGTATGATATGAGTTTGTGATTCTGAAGCATTATTATTAGCACTTTAACATGGTACCAGAGTCTAAATGTTCTTTTAAGGGATTGTGAGAGAAAAAAGAGAAGCCAAAAAGCCAAAGAGAAAAACCACACACAAAAATTCTGTGAAACAAAAATGGCTTTCAATAATTCTTTACCTTCACCTCCCAATTTTTCTAGTGAGAACTTTCATCTTTGGGCTGCAAAGATGAGGGGTTACCTGAAAGCTCAAAGGATGTGAAATACATTTGAAGATGGTAGTATTCAAACTCCATTACCTGAAAACCCAACAATAGTACAACTCAAAAGTTATATTGATGAAATAGTAAAAGAAGAAAAAACACTTGCTATCATACAAAACAACTTTACATGATCATAATATTTTGATCAAGAAGTTTGGGATCAGTTAGAACAAATGAAATGCAGGTTTTGAATATGTGAAGAGAGTTTGAAGATGAAGGACAACGAATATGTCACTGGCAGTCTTTTAAAGGGTCACATTTATAAGGTTGTTTGGTGAAGAACTAAGTGATCAATGTGTAATGGAGAATATCTTAGTTGTCTTTCTGAGAGGTTAGAATAAAAAATCTCTTCTCTAGAAGAGAACAAGGATTTCACCATGATATTAATGACAAAATTAGTAAATGCTCTACCAGTCCCTGAGCACCGAATATCTCTCAGAATGGAGGAGTATAAAAGGTGCGCTATTAACACATATCGAAGGTAAAATCCAACCATAGAAAAAACCTGTTAGTCATAGAAAAGATAAGAAGTAGGAGGATAAAAGAAGCAAGGGGAAACCAAGAGACAATATTTGTTTCCAAAACATGGCTTCGAAGGTTTCAAATGACAAACCAAACACATTTAATCTTTAACAATTCTTACTCTCATTTCCGTTTTCTTTACTTAAATTAAATCCTTTGCTGCAAGGAAAAACATCCGTGGCCTGTTTTTGGACTGTAAAAGAAGCTATTTTAATCTTATATCTATCAATTGTTGGTTGAAATGGTTTAAACGATCTAGATGAGGTTTAGTACATTTGAGTGAAAATTAAAAAAGAAAGAAAGGAAAAGCTGGCCATGCCACCAAAGCAAACTAAAAGCAATGCATTTAAGGGAGCAGTTATGATCCTTCTACATTTTTTAACATTAACAAATCCAGCAGTGTGCTTTCAGGGAAAATGGTTGTATCTGGAATGTGAGTTCTAAGTATCTAACAGTTTTGGTTAGTAGCATCTGAAATATGCTTACTGCTTAATACAGTTATTTATTACTACAGAATGCAGGTTGAGGTGAGCAAGTACACTGAAGGAGTGAATGAAAAGGCGTTACGACCAAATGGATTACCAAAGTCATTAATTCGATATGATGGTAATATGCGGAGCCATTTTTAGTAATGTCTGAATTTATGAGTTTATATGTAATCATTTAATTTCATTTACCAGCTCGTCAAAAGGAAAAAGCTTTGGGTTCCATCACCGAGGTTGTCCAAACTGTTAAGGACCCAAAATCTATTATTAAAAATAGGAGTGATGATAATGCCTCCATGCAAGAAGTGGAACAGAAAATGAATCTTGATTTTGCTTTGCCAAAGTCTGCTGTTGCTGGGAATACAAGCACACCTGGTAGACAACCTTCTCCACTTAACATCCAACGAGTGAGTTCTAATCAGGAAAAGGTCAGAACATCACGATCAGGACGGATTTCTTTCAAGGGGTATTAATTTCTTTATAGTTTAGCCAAAAATCAATTCTCATTTTCCATATGCTTAACTGGCTGCTAAAAAATATATTTTGAAAGCTTTTCTGTTTTGCTTACATTCGATTCACTAGCTATCTCCATTTGGGTTATTACCTCAAATTGAAGTTCACTGTATGTTCTTGAAATGCTTTTCCTTTCATTACAGTTTTAAAGGGAAATCTCAGAGTTATAGTGGGAGAGATGAGGAGAAGTACACTGTTGAACCTGAGATTTTGATGACCAAAGAAATAGAGTGGTCGAACAATTTGGAGAACTCACTAAGAGAGAGAGACATGAGGCAAGGAATTGATCTAGCAACCACATTGGAGCGGATAGAAAAGAACTTCGTGATTTCTGATCCTAGACTGCCAGATAACCCAATTGTAAGACAGTTTTTTTCTCTTTGGTGCAGCATGTGTATGCTGAATATATACTTGTTGTGTTTGTTGAAAATAGCTTTTAAGTGATACTATTGCTTTCTGTGCAGATATTTGCATCTGATAGCTTTCTTGAGCTTACGGAATACACACGAGAAGAAATTCTGGGACGAAATTGTCGGTATAAACTTTTCTATATCTTTGTATACAAGAGTTTCATTTTTCTTCAGTGCTGTCTTCTCTGTCAGAAACACTCTTCTGATGGATTTCTGTCTACTTTTATAGTTTGGTTGTCATTTCAGTATCACACTGTTTCTTACCAACTAGAGAAGTTGGTCTGTGTTTTTCCTGATTGTGTATTCCTCTGTCGTTTGCTAGCATTTTCTTCTATCATTTAGAAGTTCACGTTAATAGAAGAATGCATGACATACAATTTCATAAACCAGGGTAGTGATAAGTAAGAAATGTGTCAATCACCTTTGTCCTTTGAGTAGTCCCTGTACTTTTCTCTTTCAAAGAAGAATACATCATCAATTTAGTTAGAGAAATTTATTCATCAGGATAACAGGTCCTGTTTCTGACATTTTTAGATTGATAAACTTAATGTAAGCTTTTGATTGCAGTGCAAGTAATGTGATAGTTCATTTCATTCATTGCTTAGGTTTCTTCAAGGACCAGAAACAGATCAGGCAACTGTTTCCAGGATAAGGGATGCTATCAGAGAACAGAGGGAAATCACTGTTCAGTTGATCAACTATACTAAGAGTGGTAAATGACTGGTCAAATTATATCTATATTTCTGACTTTTTCTCTTCATTGGAGAATGACTTGTCTTCCCCGCAGTTGTAATTCAATCGTACACTTTCTTTATTCAATTTTTTTTTCTATTTAAAGTTGTACTTTGAAAGTTGGGTGGCAACTGATTTAGATAATATGTTTTCATTTTTCAAATCTAGCATTCTTTTTTGTTTATTTATTGTTTACCTCTTCTAATTTCTATCATGCAGGAAAGAAGTTTTGGAATTTGTTTCACTTGCAACCCATGCGTGACCAAAAGGTGATTGTGATATTGTTACGCAAGAAAACAAATAATTTGAGTCCCGAGCATTCAGTATCAAAGAATAAATTGTCTTTCCCTCTTTTTAGTTTTTATGTCGTTTTGAATGATTTGTATTTAGGGTGAACTTCAATACTTCATTGGCGTTCAACTAGATGGAAGTGATCATGTAGAACCCTTAAAAAACCGCCTGTCTGAGACAACTGAGCTACAGAGTGCTAAGTTGGTGAGTATTGTCTTTTTAGTCTTAGCTTTTCACTTAATGGTTCAAGGTGATTTGTTTTTATATTTTACTTTGTTATATGCTCTTACCCTTATTATTTCAGGACAAACCTAAGATTATGTATATTATTCCATATGTCAACAAAACTTCCGTTACTGAAAACTTCCCTTATTGAGATGTTTTCTTGAATATTATCAACCTGAATTCAGCATAACTACTATTCAATAGCAAAAATTTCTGCAATGTATTATCAAAGACAATATGTACATGATGTGTCAAACCTGTAAACATTTCAGCTGCAGTGTTCTTGTTATTTAAGAATTTTTTTTTATAAAATGTTTGAGCAAATACCCTTTCTAGATTGGTAAGAGGGGAGACATAAGAAAATATGAAATTAGTTAATTTGTATGATGGCAATAGCTGCAAATAGCCGGAATTTGTTAGTGACTATTGCCACTGTTATTAGTTCAACGTGTATTGTAATATCAATATAAAACGTTGCTCACCATGAGTTTGTCTTAGAATTCCAGTATAAAATTGAGTTGCTCATGTAAATTTCTTTACATGCTTTATTTGACTATCTTCATCATTTGCCTTTGATATTAGGTGAAAGCCACTGCAGAAAATGTGGATGAAGCTGTCCGAGAACTTCCCGATGCCAACTTGGTAAGGTATTCCATTTGGGTTAGCAATACCCCACCTGTGTACATATTTTTTAGATTTCCTGTAATGCATTATTTTATATTTGTTATAGTTGTGTCATTTGAAGAAGAGTGATATGGTATGTTTTTGCTGATATCAAATGAATCTGTTATGTTGCAGAGGCCAGAAGATTTGTGGGCAATTCATTCCCAACCTGTATATCCACGACCTCACAGAAAGGATAATCCTTCTTGGATAGCAATACAAAAGGTACCACCTACCCATTCATGCATTTCACTTCCTTTGTATGACTTTGTCCAGAGTGATGAATAAGAAATTATTTTTTTACTCGTTAGTTAATGTATAAATTAGTTTTAGTCAAGGGAAAGTTAGTTTATAAAGAGTTTTTCTAAATAAATCATTTAGCTGGCCTGTTTTGTTTTGTCGTAGAAATATGCCCTATTTTCGTTGATTTGTTTCTTTGACTTTTTCAGGTTACTGCAAGAGGCGAAAAAATTAGTCTGAAACATTTTGTGCCCATAAGGCCACTAGGTTGTGGAGATACTGGCAGGTAGAGTTTGTTATCAACCTGTATCAAATATTTGCTTTCAATAAAAGAATCCTTATATTTTGATTTATAGGGTCTAACTCTATACGAAACCAGTTCCAAAGTAGGAGTTGCCCTTCCATTATATACTTGGTCAAGATTTCAGTTTTTTCCCCAAACATTTTCTTACATCTAGCACAATTAGACTTCATAGTGAATAATATAGCAAGTTAGCCTATAAAAGATCTTGGACAATGCAAACGCATCATAATACATGACAGTGATGTGATTATCAAGTAATCAATTTCTAAGATCACCCCAAGAATTTGTGGTCCCAAAATTTTCAGTATCATAGAATAAAAGTTATCTCTTAATTTATCAAGACATCACTGTTTTTTTTGCTACAGTGTTCATTTGGTGGAACTCAAAGGCACTGGTGAACTATATGCAATGAAAGCAATGGAAAAGTCTGTCATGCTAAATCGTAATAAGGTCTGGATATGTAAGAGTCACTAGTTTCTTCTTAAAGATTCTATGTTCTTTACTTTGAAAATACATGCTTTTTGTATGAAAAGTTGAATAAGTAATCACGCTATGAATTCATGGGTTTGTTTACTTCGTATGTTCAACTTGAAAGGAAAAACCACAAATGCATAGCACAATAATGAATGCTGAGGCTTGAGAATTGAACTAATGGTTCTCAAAAACACCAACCTTGCACCCTAGTCTTTCAAATATAAGTAAAACATATTAATTTAGGCTTGTGTGTTGATGTTTCTTCACAATCTAATACCCCTTTTTCCGTTCATGAAAGTTATAGTTAACTTGTCTCACTCAACATATTTCTGTCATTAACTGATTACTATTACAGGTTCACCGATCATGCATTGAGAGAGAGATTATATCATTATTGGATCACCCTTTTCTTCCAACACTATACACCTCATTTCAGGTAAATATAACTCATCTGTCATTAAGTTGGACTGAGAGACAAGTGATGTGTAAAGTTTGATCAAGATATTGTGCTAACAGACAACCTATAATTTATTAAGCATAACTCTGGTATTCACTGGAAATGGGGAAGAACCTTTTGAAAAATTATTAATTCATGAGAAGAGTTGTACCCTGTTTTTATTTGTATCAGGCCTGTTAAATTTATAGCAAAAATTGATTGGCAAATAAAATCCTTCCGAAGACTCTCACCTATTCATCTTAATATGACTCTCTTCCAATGTTACTCTCAAAGCTACCTATAAATCGATAAAACGCTAAAACTATTGCCTACAAAATTACTATGAAATATATTGAGCAAAATATTTCTTTTAGAAAAGTCTTGAAGGATTTGTTTCCTGTAATGTGTAAAAGGTGGAGTGCTTAGTGTAGAGGTCATTATGATGTATAATACACACGAATATGGAGATATTAAAGATATTATTATCCTAAGAAACCACTAACAAACTGCTATTTACAACAGTAATAAACTGAAAAATAAGATTATTGGTAATGAGAAGGGTAAGTACAAAGTCACTAATTACATCTCTAATAACTAGGGTTCCTATCTGAGTGGGCTCTTGCCAATTGTTCTAACAGTTCTTTGTCTCAACAGACTTCTACACATGTATGTTTGATTTCTGACTTCTGCCACGGGGGAGAATTGTTTGCATTGCTTGACAAACAACCAATGAAGATTTTCAAAGAAGAATCAGCAAGGTACTTTTTAGTTTCCTAATAACACACATAATAGGCTAACAACTATTCAAAACGATGAATATATTTATATCTTTATAACGCAGACCGTTATCTTTTTTGTTAATTTTATCAATCATGTATCCAGATTCTATGCGGCAGAGGTTGTCATTGGTTTGGAATATCTCCACTTTCTAGGTAAGCTGCTCAGTATATCTTCATTTTGATTAGTTCATATACATTCTTAATCACTTTTGTATTCAATATATCTTTGATCTCTAAGCTGGCATAGGTAAAGTTCATATTATTTTCTGTGCTACTTTTGGTGTTGACTGTTAAGTTAGAATTCATTCCTTCAGCATTGCCAGTTGATCCACCTATGTATCGATAGCTTAGCAATATCATTTAGCAAAAAACCGAACCACTGAAAAGTCTAAGGTTAGAATTTAGAAGACAGTGGCAGCAAGTAATCATTTATGTAAAGCAAATCAGGAAAAAAGCAGCTTCACTTGAACTAAAAGTAACTATCAGTGTTGGTTAGGTTCAACACATTTTGAAGATATTGTATCTTATTTTTGCTAACTCTGTGATAGAACTTTAGTAAATGAGCTTTCAAAATATTTAAACAATAAAACACTTTTATTTACTTTCTCTTTATTATAACCAACTAAGGCACTTTCATTCCACACTTAGTGTTTTTTAAATTGATTTTATTCTGTTTTTGGAATGGTATGCTCTATTTCATTTTTCATGATACATACTGCATTGATTTGGCTAATTAATTTTGTTGCTGTGTTAGTTTTTGTTTAATGGTTTGATAGCGGCAAGTTCTGTTTTATGTTACTTGTCACAGACAGTCGGCATATAACAGATTATACAGTTTAATTGCTTTCATTAATTTTGATTCTGTTTATCTGCATAATAATTAGAATTAATGCAAAATGACAACATAGTTTTTAATTCTTTTCTTAAGCGAAGTGTAGCTTTTCAATGGCTCCTCTCATAAAGGGTTTAAAATAAAACTGTTACACCTTAACGACACCTTTCACTTTCGACCACCTTTCTATATATGTCTGAGTTATATCCTTTAGTGACAAGATAGGGAAACTAAGTCCAATGAGACACTGTGCATAGCTTGCATTCATCTTGAATGAGAGAGTGCCTTTGTTTTTAGTAAAAAAGACAGATCATAAAAAAAAATTTCAGGTTTGTTGTATCCCAGGATTTTTCCTGTCTTGCCTGTTTTGGGGTTAGGGATGTTTTTCTTTCCTTACAATTTTTGCATGTATTTATCTTTGTGTTTAATCATACCGTTACCATTTTTTTTTTAATTTTGTATGTTATGCCAATATAGTCCATGTGATTGTTTTGGAAGCAACCTGTCCTGATAGAATTTTTTTATTATGCACAACAATGAGAGAAAAAGGTAGACACTGAATCTTAGGTTATCTGAATATTGTTTTCTTTTATTGAACCTGTCTAGGTATAATTTATCGTGACTTAAAGCCTGAAAATATCTTACTTCAGAAGGATGGTCATGTTGTATTAACTGATTTTGATCTATCATCTATGACATCGTGTAAACCCCAGGTACGTATACTTTATTCCTGTATAAACATGGTCAATTTTTTGTAAGTTATTGGAAATTCTTGACTAATATTTGAAATTAATTGGTGTTACACTTCTCCAATGATCTAGTTGTGGTAGAAAAAAAGTGTTTCCCAAGGCTTTAAATCTCTCCACTTTTAATATAATACATTTTTTTACTGATGTTTTAAAAACAATTTTGTTATTGTTGTCTTCTTTTGGAGTCACCAGGTATCTCTAGTAGTGGCACTTTTCTTAACCATCATTACATGAAAAATATGTCTTGCCCTTAGATAAGAAAAGTAACTGATGTACTAGGGTTGCCTTTCAGCTTGATAATTTGTCAGATGCTTAAATTAAAATTCAATTTTACAGGTTGTGAAGCAAGCATTACCTGGTAAAAGAAGAAAATCACGAAGTGAACCTCCACCAATACTTGTTGCAGAGCCAATTACACAATCAAACTCATTTGTTGGAACTGAAGAATATATTGCCCCTGTATGGCGATTTTCAATTCTTCTTCATTCACAATCAAACATGAGGACCTGTATTGTAGTCCATTAAAATCATAATAACATTATTTTGTTATTCATTTGTTGTTATTTGTTATTATCACTGTCATTATCATCTTTTAAGCTTTTTAAGGTACTTGATTTCAGGAAATTATAACTGGAGCTGGGCATACCAGCGCTATAGATTGGTGGACTCTTGGTAATCACTTTTATCCTTATGATTGAATACCAACTATGAAGCTTTATTTTGTTACTAATTGTAAGAAGTCTCATGGGGATTAGAGATAAGACAATTTAGAGCATATAAATAGGTGTAAACCTCACTTTAAAAGTTGATTTTGTAGGGTTGAGTTAAGTTTAAAGTTCACCTCTTAACATGGTATCAGAGCCATTGAACCACCTATTAATATCTAGTCTCACACGTGAGATGTATATACCTCGGTATGAAGGAGTGTGTTGGAAGTCCTACCCCTACTAGAGACAAGACCAATTTAGTTTCTGTTACCTGGAACAAAAATAATTACTTCTCGAAAATTTTGATAGAGCCTACTTTATTGATGCTTTGTGCATAGAGGGGTTTTGCTTGACGGGGCATATTAAAAGTCAAAGCTATTCCTTGCATCCCCCTAATAAGTTTTAGTCCCAAATGGTTCTTAACAAAGACACAAGGATTCAAAAGAGTAGGTTTTTTTTTTTCTTTATTTTTGACATTAACAATTCTGTTTCTTTCTGTTTAGGTATCTTATTGTATGAGATGCTGTATGGTCGCACACCATTTAGAGGAAAGAATAGACAGAGGACATTTTCCAACATCTTACACAAGGATCTTACCTTCCCAAGCAGCATCCCGGTACACAAAAATAGTGCTTGATTTTTATTAGTTAAACTTAGAATTTTCTGCATAAATTACATGTAATTCCCAACTTCAAACAATGGGTAGTAAAACTGATGTAGAAAATCATAAGTTCATAACCACTCAAATAGATAGGTACTTGATTTCAAATTCCTCTATAGGTGTGAAAAATAGTACATTGTATTGACAGAGGAAGTGGTCTTTTGACATCCATAGATACATTTCACAAAAAGTGTGCAAATTATCATAATTCACTGTGCTACTGTTTTTATCTTACTACATCAACTGATACAGTTCAAAAAATTTTCAGGCCAGTCTTGCGGCCAGGCAGTTGATTAATGCATTACTGCAGAGAGATCCAACAAGTCGTCTAGGTTCAACCACTGGTGCAAATGAAATCAAACAACACCCTTTTTTCCGTGGAATCAATTGGCCTCTAATCCGCAACATGGTAAAATCCTTGTCATTACTTTTCAAGTCAGTGATTAGAAAAATATTGATTTCCACAAAAATCCCTAAATATCCATTTACTTGGTCAATTTTGAATTTATAATCCAAATCAGTCCATAAGGTCCTGATGTGGGGACTACTTTGGCTGACAAAATGTACATTCAAGGACCTCAAGAACAATGAATCTGTATCACTCAACTTGACATGTCATATCTCTGTAGAAGCCAATTTAGGGTTGGTTAAAGTAGTGGAATTGAATGCGACAGCTACTACCCTCTAAGCCTTTTAAACCAGAAAAAGAAAAAGAGAAAACAGGCAGTCAAATAATGTTTTTAGTACTTGTTGAAGTTGTTACCTGCTTATGTTCCTATGTATTTGATGCAGAGTCCACCTCCATTAGATGTTCCTCTAAAATTGATAGGAAAGGATCCAGTGGCGAAGGATATAAATTGGGAAGATGATGGAGTGCTAGTTAGCTCCATTGATATGGATATTTTTTGACGGCTCAGTGTTTACTTTACTGATATGGATGTTATGTCAGCGTCATCGTATCTGCTGCAACAATCACGGGGTGATGTTAAAGTGTAATATATAGAGTATCTGTTGATTTGGTAATGGTTCAAAATCTAAGTTATGTAGGATTAGCAGAAAATTAGAATGTACAATGTACATTGAACAAGCATCTAGTTATGCATGTCGACAATACATCAATAATATACTTCTGTAGATGCCTTA