Gene Details:

Gene ID Chr. No. Start Position End Position Function View on
Vu_28607 LG8 11573855 11586753 PREDICTED: serine/threonine-protein kinase Aurora-3-like isoform X2
Map

Annotations  
category   relationship type   keyword
Biological Process   involved in   mitotic spindle organization, phosphorylation, histone phosphorylation, histone H3-S28 phosphorylation, regulation of cytokinesis, histone H3-S28 phosphorylation, mitotic spindle organization, histone H3-S28 phosphorylation, histone H3-S28 phosphorylation, histone H3-S10 phosphorylation, histone H3-S10 phosphorylation, histone H3-S28 phosphorylation, histone H3-S10 phosphorylation, histone phosphorylation, histone H3-S28 phosphorylation, chromosome segregation, regulation of cytokinesis, histone H3-S28 phosphorylation, mitotic spindle organization, histone H3-S28 phosphorylation, histone phosphorylation, phosphorylation, histone H3-S10 phosphorylation, histone phosphorylation
Cellular Component   is active in   spindle midzone, spindle microtubule, spindle pole centrosome, spindle microtubule, chromosome passenger complex, spindle pole centrosome, spindle midzone
Cellular Component   located in   nucleus, spindle, nucleus, spindle, nucleus, chromosome, centromeric region
Molecular Function   enables   histone kinase activity (H3-S10 specific), histone kinase activity (H3-S28 specific), histone serine kinase activity, histone kinase activity (H3-S10 specific), histone serine kinase activity, histone kinase activity (H3-S28 specific), protein binding, histone kinase activity (H3-S10 specific), histone serine kinase activity, histone kinase activity (H3-S28 specific)
Pathway   B 09181 Protein families: metabolism   C 01001 Protein kinases [BR:ko01001]
SNP Position Effect Amino acid change
A/G 11573947 synonymous_variant p.Lys31Lys
T/G 11574104 intron_variant
T/A 11574132 intron_variant
T/A 11574140 intron_variant
C/T 11574418 intron_variant
T/C 11574452 intron_variant
G/C 11574760 intron_variant
A/C 11574761 intron_variant
C/T 11575163 intron_variant
A/G 11575334 intron_variant
G/T 11575452 intron_variant
A/C 11575491 intron_variant
C/A 11575842 intron_variant
C/T 11575885 intron_variant
G/T 11575903 intron_variant
A/C 11575947 intron_variant
G/T 11576017 intron_variant
T/A 11576073 intron_variant
G/A 11576100 intron_variant
A/T 11576134 intron_variant
A/T 11576210 intron_variant
A/G 11576213 intron_variant
T/C 11576215 intron_variant
T/C 11576217 intron_variant
C/A 11576223 intron_variant
A/G 11576225 intron_variant
G/A 11576235 intron_variant
C/T 11576238 intron_variant
C/T 11576245 intron_variant
A/G 11576280 intron_variant
A/G 11576292 intron_variant
G/T 11576295 intron_variant
C/T 11576311 intron_variant
C/T,* 11576322 intron_variant
T/C,* 11576328 intron_variant
C/T,* 11576346 intron_variant
C/A 11576363 intron_variant
C/G 11576420 intron_variant
C/T 11576423 intron_variant
G/A 11576429 intron_variant
C/T 11576431 intron_variant
G/A 11576500 intron_variant
C/A 11576506 intron_variant
C/T 11576514 intron_variant
T/A 11576547 intron_variant
T/C 11576551 intron_variant
A/G 11576554 intron_variant
C/T 11576563 intron_variant
C/T 11576564 intron_variant
C/T 11576567 intron_variant
T/C 11576579 intron_variant
C/G,T 11576592 intron_variant
A/G 11576596 intron_variant
G/C 11576598 intron_variant
C/T,A 11576603 intron_variant
G/A 11576614 intron_variant
A/G 11576619 intron_variant
G/A 11576638 intron_variant
C/T 11576814 intron_variant
G/A 11576821 intron_variant
C/T 11576842 intron_variant
A/T 11576847 intron_variant
G/A 11576849 intron_variant
G/A 11576865 intron_variant
G/A 11576875 intron_variant
G/T 11576878 intron_variant
C/T 11576891 intron_variant
A/G 11576895 intron_variant
G/A 11576903 intron_variant
A/G 11576911 intron_variant
C/T 11576912 intron_variant
T/C 11576913 intron_variant
G/T 11576975 intron_variant
A/G 11577012 intron_variant
T/G 11577018 intron_variant
T/C 11577030 intron_variant
T/G 11577051 intron_variant
T/C 11577070 intron_variant
G/A 11577081 intron_variant
A/T 11577099 intron_variant
A/G 11577182 intron_variant
A/G 11577190 intron_variant
G/C 11577263 intron_variant
A/T 11577312 intron_variant
C/T 11577476 intron_variant
A/T 11577523 intron_variant
G/A 11577944 intron_variant
G/T 11577981 intron_variant
A/G 11577986 intron_variant
G/A 11578059 intron_variant
G/T 11578339 intron_variant
G/T 11578598 intron_variant
T/G 11578612 intron_variant
A/G 11578870 intron_variant
C/T 11578873 intron_variant
T/G,* 11579078 intron_variant
T/C 11579221 intron_variant
G/T 11579335 intron_variant
G/A 11579488 intron_variant
G/A 11579544 intron_variant
G/A 11579562 intron_variant
G/C 11579588 intron_variant
G/A 11579594 intron_variant
G/A 11579685 intron_variant
A/G 11579827 intron_variant
T/C 11579850 intron_variant
G/A 11579885 intron_variant
T/A 11579890 intron_variant
G/A 11579985 intron_variant
C/T 11580007 intron_variant
T/G 11580031 intron_variant
G/C 11580032 intron_variant
G/A 11580043 intron_variant
T/C 11580044 intron_variant
C/G 11580045 intron_variant
C/A 11580046 intron_variant
G/A 11580052 intron_variant
C/A 11580053 intron_variant
G/A 11580072 intron_variant
C/A 11580074 intron_variant
A/G 11580076 intron_variant
G/C 11580084 intron_variant
A/C 11580091 intron_variant
T/C 11580102 intron_variant
G/C 11580103 intron_variant
A/G 11580106 intron_variant
A/G 11580108 intron_variant
A/G 11580129 intron_variant
T/C 11580136 intron_variant
G/T 11580137 intron_variant
C/G 11580272 intron_variant
A/G 11580366 intron_variant
T/A 11580375 intron_variant
G/A 11580448 intron_variant
T/G 11580635 intron_variant
C/T 11580636 intron_variant
G/C 11580670 intron_variant
G/A 11580681 intron_variant
C/T 11580682 intron_variant
A/G 11580738 intron_variant
G/C 11580854 intron_variant
G/A 11580932 intron_variant
A/G 11580933 intron_variant
A/T 11580936 intron_variant
C/A 11580939 intron_variant
G/A 11581009 intron_variant
C/A 11581065 intron_variant
T/C 11581093 intron_variant
T/C 11581100 intron_variant
G/A 11581151 intron_variant
C/T 11581231 intron_variant
T/C 11581236 intron_variant
T/C 11581240 intron_variant
C/G 11581245 intron_variant
T/G 11581259 intron_variant
T/A 11581271 intron_variant
A/G 11581280 intron_variant
C/A 11581284 intron_variant
A/G 11581300 intron_variant
A/C 11581330 intron_variant
C/A 11581377 intron_variant
G/C 11581437 intron_variant
T/G 11581529 intron_variant
G/A 11581599 intron_variant
T/A 11581603 intron_variant
T/C 11581619 intron_variant
T/C 11581627 intron_variant
A/T 11581635 intron_variant
A/G 11581640 intron_variant
T/C 11581644 intron_variant
G/A 11581645 intron_variant
A/T 11581651 intron_variant
C/T 11581657 intron_variant
A/G 11581696 intron_variant
G/A 11581697 intron_variant
A/G 11581703 intron_variant
C/A 11581710 intron_variant
G/A 11581712 intron_variant
G/A 11581715 intron_variant
T/A 11581718 intron_variant
T/C 11581723 intron_variant
C/T,A 11581745 intron_variant
T/A 11581768 intron_variant
G/A 11581776 intron_variant
G/A 11581777 intron_variant
G/A 11581783 intron_variant
A/T 11581784 intron_variant
G/C 11581785 intron_variant
T/C 11581797 intron_variant
G/A 11581798 intron_variant
A/T 11581802 intron_variant
G/T 11581804 intron_variant
T/C 11581808 intron_variant
G/A 11581820 intron_variant
C/G,T 11581830 intron_variant
G/A 11581911 intron_variant
A/T 11581998 intron_variant
C/T 11582082 intron_variant
C/T 11582168 intron_variant
G/A 11582169 intron_variant
C/T 11582185 intron_variant
A/C 11582238 intron_variant
C/T 11582266 intron_variant
C/T 11582373 intron_variant
T/A 11582420 intron_variant
T/A 11582444 intron_variant
G/C 11582482 intron_variant
A/T 11582525 intron_variant
G/A 11582596 intron_variant
T/A 11582598 intron_variant
A/T 11582604 intron_variant
C/T 11582671 intron_variant
G/A 11582779 intron_variant
A/T 11582863 intron_variant
G/C 11583020 intron_variant
T/G 11583030 intron_variant
G/A 11583183 intron_variant
G/A 11583248 intron_variant
G/A 11583410 intron_variant
A/T 11583537 intron_variant
T/C 11583823 intron_variant
G/T 11583824 intron_variant
A/G 11583826 intron_variant
T/A 11583835 intron_variant
G/A 11583871 intron_variant
T/C 11583944 intron_variant
G/T,* 11583970 intron_variant
A/G,* 11583999 intron_variant
T/A 11584005 intron_variant
A/G 11584022 intron_variant
A/G 11584026 intron_variant
G/A,T 11584032 intron_variant
G/A 11584038 intron_variant
G/A 11584041 intron_variant
A/T 11584042 intron_variant
T/C 11584085 intron_variant
G/A 11584107 intron_variant
G/T,* 11584115 intron_variant
G/A 11584118 intron_variant
T/C 11584121 intron_variant
G/T 11584123 intron_variant
G/A 11584130 intron_variant
G/A 11584140 intron_variant
A/G 11584141 intron_variant
A/G 11584143 intron_variant
T/G,C 11584154 intron_variant
G/A 11584161 intron_variant
T/C 11584166 intron_variant
C/T 11584174 intron_variant
G/A 11584175 intron_variant
G/T 11584191 intron_variant
C/T 11584197 intron_variant
C/T 11584203 intron_variant
G/C 11584213 intron_variant
C/T 11584222 intron_variant
C/A 11584236 intron_variant
G/A 11584244 intron_variant
T/C 11584291 intron_variant
T/C 11584398 intron_variant
G/A 11584515 intron_variant
T/A 11584523 intron_variant
A/T 11584533 intron_variant
G/A 11584539 intron_variant
G/A 11584542 intron_variant
A/G 11584556 intron_variant
A/G 11584578 intron_variant
T/A 11584644 intron_variant
G/T 11584646 intron_variant
A/T 11584651 intron_variant
C/T 11584739 intron_variant
A/T 11584815 intron_variant
C/T 11584823 intron_variant
C/T 11584926 intron_variant
C/T 11584927 intron_variant
T/C 11584938 intron_variant
G/A 11585010 intron_variant
C/T,* 11585047 intron_variant
G/T 11585048 intron_variant
G/T 11585098 intron_variant
C/T 11585126 intron_variant
A/T 11585150 intron_variant
T/A 11585193 intron_variant
G/A 11585237 intron_variant
G/A 11585267 intron_variant
G/C 11585273 intron_variant
C/T,* 11585364 intron_variant
C/G 11585412 intron_variant
C/A 11585878 missense_variant p.Ser195Tyr
C/A 11585933 synonymous_variant p.Ala213Ala
T/A 11586085 missense_variant p.Leu236His
C/G 11586088 missense_variant p.Pro237Arg
G/T 11586274 missense_variant p.Met266Ile
T/C 11586338 intron_variant
G/T 11586458 intron_variant
G/A 11586606 intron_variant

View accession wise SNPs


Sequence Details:

Protein Sequence:
>Vu_28607.1
MASQNPAEDENSKQNWSLQDFEIGKPLGRGKFGRVYVAREVKSNFVVALKIIFKEQIDKYKIHHQLRREMEIQTSLRHPNILRLYGWFHDTDRVFLILEYAHKGEVYKEMRKKGHFTEKQAATYILSLTKALAYCHEKHVIHRDIKPENLLLDHEGRLKIGDFGWSVQSKSKRHTMCGTLDYLAPEMVENKAHDSAVDNWTLGILCYEFLFGAPPFEAESQADTFKRIMKVDLSFPSNPSVSLDAKSLISRLLVKDSSRRLSLQKIMEHPWIVKNADFSAELLQRVLQF*


CDS Sequence:
>Vu_28607.1
ATGGCTTCTCAAAATCCAGCGGAAGATGAAAACTCAAAGCAAAATTGGTCCCTCCAAGACTTCGAGATCGGTAAACCTCTCGGCAGGGGCAAATTTGGTAGAGTTTATGTTGCCAGAGAAGTCAAGAGCAATTTTGTTGTGGCGTTGAAGATTATATTCAAGGAACAAATTGATAAGTATAAAATTCATCACCAACTAAGGAGAGAGATGGAGATACAGACCAGTCTTCGGCACCCTAATATCCTGCGTCTTTATGGTTGGTTTCATGACACTGACCGTGTTTTCTTGATTCTCGAGTATGCTCATAAAGGTGAGGTCTACAAAGAGATGAGAAAGAAGGGTCACTTTACAGAGAAACAAGCTGCTACGTATATTTTGAGCCTCACAAAGGCGTTGGCTTATTGCCACGAGAAGCATGTTATTCATAGGGATATCAAGCCTGAAAATTTGTTGCTGGATCACGAGGGTCGTCTTAAAATTGGAGACTTTGGTTGGTCTGTTCAGTCTAAAAGCAAAAGACATACCATGTGTGGCACATTGGATTATTTAGCACCAGAAATGGTTGAAAATAAAGCTCATGACTCTGCTGTTGATAACTGGACTCTTGGTATCCTTTGTTATGAGTTCCTCTTTGGTGCCCCTCCATTTGAGGCTGAGAGTCAAGCTGATACCTTCAAAAGGATAATGAAGGTTGACCTAAGCTTCCCTTCCAACCCTTCTGTTTCTTTAGATGCCAAAAGTCTGATTAGCCGGCTTCTGGTGAAGGACTCCTCACGAAGGCTCTCTCTTCAGAAGATAATGGAACATCCTTGGATAGTCAAGAATGCAGATTTTTCGGCGGAGCTGCTTCAAAGGGTGCTGCAATTCTAA


Promoter Sequence:
>Vu_28607::LG8:11571855-11573855(+)
GTCAAGTGTATCGAAACACAGTTTCCCCCCACTCAATTGTGGAGGTAAAAACTCTTATAGGTGTTTGAACCAAGGTAGTTCAAGTTCATGACGATTTTTGCACAACTCGTAGAGCAAGAACTTATTAACTTCCGCAATCAATTTGATCGACAACCACCTTCTTATATTACATTACATTGTATACTATTATGTACCTTTTCATTTCAAAACTTGTTGTTTCGGGAAATGTCATTACGTTTTTTTATTAATGTAAGTGCTTTTTAATATTGTTATAATTTTTCATTACTCAATACCCTTAATTATTTCTTTTATATTTGTTTAATATTGAAGTATTCCAACTTGAAGTGTTCCATTAGTGATCCATCCACAAAACTTTCAAAAGACAGTCATAACGAATCCAAAATATTCATGGGGAGTGCTTAAGCCACGTTTGGGTAGCACTCTTCAACTTTCAGTACAAAAGGGGATTTTTCTACTGGTAAGCGATTACCAGCTCCCTGTAATCGATTACAACAACATCAGTCCTGTGTCAATGGTGCAGGAACTCACCTCTCAACCTAGAAACACCTTAACTTGGTCTTCCATCCACATAGGACTGACCTAACTTGAAATTTCTTGTTGTGAACACCTTCAACCATGGCCAACAGGGATAATCAATCCACACAACATTGAAAACATACTCGTAAGGACCCCTGGATAGTGTTTAAGCCATGTCTGGGTAGCACTCTTCAACTTTCGGTACAAAAGGGGATTTTTCTAAAAGCATCCAAATTGCGTCTTCGAAATAATGGACTTGTGCTCCTCACTCAAAATTCCATTCAAAGTAGCAATACACTTTGTTTTCAATGATGACGAACAAACAACTACAAAAAAAAAATATTTGTTAGTACAAATAGCCAACAAAAGTCACAACCCAAAAGCAAAAACCAGCAAAATGTCCAACAAAGGCCAAAAGCAAAAACCCAACCCCAAAATACGAATACGGAAAGGGAAAAGTTCATACCTTGTTAGAAGAACTAATGTCAGCAGACAAACCCATTGCACAAAAAAATCTCAGAACTTTGACAAAATCGACACCGAACGAGACACTTTCAACAAACCAACCACAGAGATCGCTGAACGTATATCGTTGAAATCACGAACTCGAGAGAGAAAGAGAGACTTTGAGGCCACCGACGACGGAACTTCCTCAACGTCCAGAGAGATTGCTCAACTTCACCAAATGGAGGGAGAAAATATCAAATGAAAAAACTGAAAACCTAAAATGGAGAGAGCAGAGAGTGTTTCGGAACAAGGAGAGAGTGCTGAAAGGAAGGAGGGTGGTTTCGGAATAAACAAATGTTCAACCATGACCCCTTTTCCAAATCGGTTTTTTTAAAAAAAATAATTTCAAAATGAGCCCATACAACGCTGACACGTGATGTTGTCAAAACGTTGTTAAATTCGCATTGTCAATGTATCGCGATCCAAAAATTTAAATACTTCAGTGTTAAAATCTTTAACCGAAACCTATTATACCAATTACTAAATTGAAACTTTAATTTTGATGAGAGAACACCAAAAGCACTAAGGGATTTCTATCTACGTTTTGTCCTTGGCATTATACTTACTTTATATGTTAATATTGGGTTTTCGTTAAATTTCCTTTTTAAGTATTTGGTTGAGTTAAATTTTTAAGTATCTCACCTATCCATCTTTGTTAGCAGCAGCACTCACTAGAGCTCAACTATTCTTTGCTTCCGCCATGCGTTCTTCGCCCTTTCACCGAATAAAATCATGATTTCTTTCCATTCCTTTGATTTAATCGGTGAATCCCTCTTTTCCACCGATTAGATCTCTTCTTACCTCTAACCCTAAGATCTACACCGATCAAACCTTCGAAGCCTAGGGTTCTTGAGTAGATTCGTTTTCTTCCGTTCGTTTCTTCAGCTCGATCAAGTCCAGATTTCATGTTTCTCGCTGATGTGCCTCGAGCCGCATTTTGCATTTTCCTCCAAAAA


Gene Sequence:
>Vu_28607(+)
ATGGCTTCTCAAAATCCAGCGGAAGATGAAAACTCAAAGCAAAATTGGTCCCTCCAAGACTTCGAGATCGGTAAACCTCTCGGCAGGGGCAAATTTGGTAGAGTTTATGTTGCCAGAGAAGTCAAGGTTCTTAATTCTCGCTTCATTCCTATTTTCTTTAACATATATTCTCTGATTCATTCAAGTAATTGAAATATTAGAATGTTCACTTAAGCAATGATCTTTAGAAGTGTAGATTTTGTCCTCTGATTAGCCAATAGAGTTAAATTTTTGTATTTAATATAATTTGAGTTTGTTTTCAGAGCAATTTTGTTGTGGCGTTGAAGATTATATTCAAGGAACAAATTGATAAGTATAAAATTCATCACCAACTAAGGAGAGAGATGGAGATACAGACCAGTCTTCGGCACCCTAATATCCTGCGTCTTTATGGTTGGTTTCATGACACTGACCGTGTTTTCTTGATTCTCGAGTATGCTCATAAAGGTGAGGTCTACAAAGAGATGAGAAAGAAGGGTCACTTTACAGAGAAACAAGCTGCTACGGTAATCTATTTTCTCAAGCGTGTGCAATGTTTTGAAGATCTTTCATAATTCATGAGGGATTTTCTTTTTCCTTCGAGCTTACCAAAATTGATTTGTGTACTTTGGTTTTTGAAGAAATTACGAGTTTTCTGAAAGTTAAGTTTATGATTGATTTTTGTATCGGAGAGAAATTCAATTTTTACCATCTTATTCTCTTACCCTGTGAGTGTTTGTAGAGAAGTTTATCCAAATAGAACCTAGCTCTATCATTACTTTCCTCTGGCTTGATTTGGAGGAAGCTTTCATCTTTCTACTTGCAAGGAAGATAAATGTTTTTAATTGGTTCTTGCCATTTTTCAATTATTGGGTTTTAATTCTTGAGAAAAGATGAGTATGAGAAGAAAGCAGCTGTAGTTTTTCTAATTTTAGAAATTTGATTTTTGTTTCTGAAGAGGTTGAACAGAATGCAAAGTCGGAGTAATCTTTGAAAAGTTTTTTAAAAAAAAATTATGAGTTGTTTATGATGACTGCAGCAGATGTACTAGTTGTAGTGGCCTGCAGTGTGAAATGTTAATTTAGAGCAATGATACACATACACCTCCATATTATCAATACCTATTCTATACTTATTTTTCTTTCTATCTCTCTCTTCTTATAACCTATAACCTATCATTTTTACTCTCTCTAGGTGTATATTAAGTGTTGATGCACCTTTTTAATATTCATGAATCATTTTTCATTGATTTATAGAGATGTTAATTGTGTAAACTTCGTGAAAAGTCCACGGAGTCGTTTTTTTGTGTATTTTTTTCTACGTGATTTAAATTAAAAGATATGTATACAAATTATGGATATTTTTTGTATTTTTTGAATTAAAACAAGAAAAAAACAATATTTTAGGGATTTTTGCGAGCAAATGATAATTTTTTCGGAAGTACTGAAAAATCGTGCAAGAAAATTCCTTTTGTTTATAAAATAAATAAATGGACACTATGTTATATTATATTTTGGACAAGGCTGCGTTATGCATCAGGATCTAACAAAAGATAAGAAGAAATTTCAAATTTTCATGTGTCTTTCTTCTTACACAAATAGATCTTATGAAGATCTTGAATTGTTTTTGTGAGTCAATCCCTAACTGACATTTGTCTCTAATTCTAACGAAAATATTCCCAAGTATTAGATAATGACATTGACATCTAATATCTAGATGCAATTTTTGAACTTTTGATATTTTCGTAGTGGGCCTTTATTAAGATATTTTAGGAAGTTTCAGATTTGATTTCTATTGTTTTTAATTTTGTCTACTGGGTGTATTATGTTTTTATTTCTAGCATATCACTCCCACAATATTAGGAGGTGAAGGGAAGCATGGTTGTGTAAGAGTTTGGTTGTACCGTGTAGGGTTATGAGGGAGCCATTGTGAGTAAAGAAAGTTGGGTCTGGAAAAATTGGCCTATAAACGGTTTAGAGAATGTAACCAATCCATACTGAGAATCATGTCAGCTCCTTCCAAAGGAATGAGGTAGAAGTGAATAGTTAATGTCTGTGTTTGGATAAAAACCATGACATTGGGACAAAGGAAAAAACATCGGATTCTTTCCCATTGCCAACCATAACGGAGAAACATTGAATAGAGATAGTACAAAGGTGAAGGTGATGGGCTACGTGGGTTTGTAAAATGTTATAGGAACTGCTAGTATCAATTAAGATTTTAATCGGGAAGTTGTTGATATGGCCTTGAAACTTGTTAGAAGTGGACTTTAAGCCTAACTCAACCCCACAAAACAGGCTTGTAAGGTGAGGTTTGCACCTCACTTATATATTATAAATTAGTCTTATCTCTAGTCGATGTGGGACTTCCAACACACCCCCCTCACGCCGAGGTATATACATCTCGAACGTGGGATTAGACAGTTTTAATGGGTGGTCCGATAGCGGTCCGATAGTGGGTGGAACAATATGCCCAGTAAACAACAAATATCGCTAGGATAGGCTCGAACCATGACTCTGATACCATGAGCTTTGATAGGTCCTTCGACTCCTCGACGACGCACACAAAACTCTCGAAATCATCTATCAATGATTTCAAACTCTTCTCCACAACTCGACTGGCAGGCAGCGACTCTCCATTTCTGCCGAGTTGATCTGCCACTTTCTCCTTCAAATTTTTAAATTCCCCTTCCAGCGGAAGCATTCCTAACCAACCCCAACTACAAGTAGCCCTTTCCAACCGCCGTATCTTAACGGAACTTACCTGGATACCCTTTGCCAGGAAGACTTTCGGTATAGGGATCATTATACTCGTCTGACCTAGTCACCAAGAGAAACCATTGGCTCTGATACCATTGTTGGAAAAAATGTGACCCACATAAATAATAATACTCTTCATTTCAAGCGAGTTCTATGTGGGCATTCTATTCTTCTATTCCACCCGTTATCGGACCACCCAATTTCTACTATCACGCACGAGATGTCTATACCTCGACGTGAAGGGGGGGTGTTGGAAGTCCCACATCGACTAGAGATAAGACTAATTTATAATATATAAGTGAGGTGCAAACCTCACCTTACAAGTCGGTTTTGTGGGGTTGATGTAGGCTTAAAGTGCACTTCTAACAGATATCAATACAAATTCATTCTTTTGTCATTTGTGTTCTTGTTTGGGTGTGTGTGTAGAGTTTAGATAGGTTTCATATTCAGAAACCTATCAGTGTTGAAGATGGACTTTGAGTTTGTGGTAAGGGACTTTAGGAGGGTTGAGGAAGGGTGTTTAGGGTTCATGTATCGGAATCGTTATTTTAGATTCCAAAAGCTTGGCAAGACATAGAGCTTGGGTGATTGAAGTGGGTTGAAGGACAACTACTTCTCTGTGAATCTCAGGGATGAGGCCAGAGATTAGACAATTAAGTATCATCTCGGGAGTGAGGCCCAAAACACTTGGAAAGTTTTTCAAATCTGTTTGATATGCTGTAACAGTGCCATGTTGGCAGAGTTTGAATAGCTTGGCCTAATTGTTGGCATATGTTGATGGGCCAAAACGAAGTTCTAGAGCATGATTGAAACAATTCCAATCACTGAGTTGTTGATTCTAGTACATCCACTTGAGCCAACTGAGTATCTCGCCTTTCATATAAAGAACAAACATGTTTAATAAAAAATCCTAAGAAATATTATAAAATTCAAAAAATTGGTCAGCTTGAAATAGCCAATCTAAGGAATCTGTTCCATAAAAAAGAAACATATGGATTTTTTGGTGGATAGATAGGGGAAGGGATTGATGGTGGAGGAGAGTAAAAAGGTGGAATGGTGGTGGTTGTTGCTGTAGTAAAAATGGTCTGGAAAATATTGGGAATTGGGGTGGAGTGGAAGGCGTGGTGCCTATGGACATATTGAAGAGTGTCAAAAGGTATATTGTGGGGTGGTATTGTGGTAGTAGTATGAGAAGATAAGGTGGATAGTAAAGTAGTGAGCGCATGGTTGATGGTGTCGTGCTTGGTTTCCAAAGCCGTTTGATGAGATTCCAAAGCTTGTTGAAGGGTGATGTAGCGACCATCGTGGTCTTGAGTAGTGAGAAGTTGTGTTTGAAGGTTGGCTAATTTGTCCAAAAAGGTATCCAAGGTTTCATCTGGGTCATTTTTTGGTTTAGGAGACATGGAAGTAGGTCATTGAAAGCCCCAGAATGTTATGCACTGGAAAGAAGATGAAAATAAACTGATGAAAGATATGAAGAAAATGCAAATTTTACTCTCTATCTTTCTTGTTACATGGATAGGTCTTATAAATACCTTGAATTATTTTGGTGAATAAAACCCTAAGAGGCATCTGTCGCTTATTCTAGCATAAAATATTTCCAAGTGTAACATAATAACAACTAATACCTAGATGTACTCTTTGAACCATATGGGCTTTCATATTTTTCTGGTGGGCCTTGATTACTCTGACATGCTATCACTTTGTGTCATTATCTTTGTTTGCTCCTTTATTGAGGTAAATTGTTTTATGTTGACTCATAACTCGTCTTTTATTTTTATAATTCCAGTATATTTTGAGCCTCACAAAGGCGTTGGCTTATTGCCACGAGAAGCATGTTATTCATAGGGATATCAAGCCTGAAAATTTGTTGCTGGATCACGAGGTATGCTAAAATATCTTTCCTCCGCCAACGATGTATTTTTCCACACTAGTGTTCACTTATGGCAATGTTTGGAACTCTCGTGCCTAGAGTTTTAGTGTAGGTGCTCGAATCTATTTTTTGCTGTAATGCTAAAAGATATTGATGTCAAATCTCTAATGCCCTTTCTTGAAAAAGAAAATGAATTTTATTATTTTCATTCATGTCTATTACATTCTCCTTACCTTTATTTGTAACAATCTAATCTTCTAAAAAAAGGAAATAAGGAAAAAACATACTGAAATTAAAAACAGAACGGAACACACACTAACGACACAAACACACCAAACAGAACACAACAAACACTAACGACACAAACACAGATATTAAAAACAGAACACACACACACTAAACAAAACATAAGACAGAACATTGGTCCCCGGCGACGACACCAAATTTGATGTTGAGGCCGCACCCGACTCAAATTGAATTGTGCAATTAAGTGCAGTATACTAGGATGTGATTTCTAGGTCGTCCCTTAAGGACTAATTTTGGTTCCGTCAAAGGATCAAACACGTAGTGGGGTTTTTGAGCAGATCTACGAATTGAAATTAACATAGCAAACAACTTAGACTAAACAATGATTAAAAACAGGTTGGCTACTAGTTCAATTGCAATGCTTCCAATCCTGGATTAGCAATAATTCATCCGCTCCTCTCACCACTAATTCAACACAAATTAATCAACTAAGTGAAGATTAAAACGGTTTTCATAATAGTGAATTAAGCAAACGCAATGCACATATTTAATCACTTCTGCGCCACCACAGATTAAGCAACTGCGGCTCTAATCAATTAAGCGGAGATTAAACACAAATTAGACCACTAAGTGTGTACCTAATTGCAAGCACATAATAGATTACATATGATGCAAGGTATGAAGAGCAAAATCACATTGACAGTGCAGTAATCTCAAAGAAGCAATGCAATCTCCCTGGTTACCAACCCAGCAGATTCAAGCTTTCACTAAAACGAATTGGAAACAGCAAAACGAATTGGAAAACATCAGAGACAAAGGAGAACGAAATTGGAATACGAAAATGAACTGGAACACGTGAAACTGGAAAATGAAAGTGCAGAAGCAAGAGCAGTAAAATGAAATTGCAATGAAAACGAAATTAGAATGAAAACTGGAAAACGACAAATACAAAAACCTAACACAGAGCAACTCTTTACATCCCAACACAATGGAATGGAATAAAATGTTTCAAAGTTCAACTGCATGGGTACAAAACCCTAGGCAACAACCCTTAAAATGGGCTTCTCCCTAATACTAAAAATGGGCCCAAAGTTTAAGTTGGACCCAAAATACAAAGGAAATAAAATTCCAAACGAAATTAAAATAAAACGCTGAGGTGGACGATGGTAGATGACGTGGTAGCCCTCTTGAAGTCCAAAATATAATTCTAGAATTGCCCTAAAAGTAATAATGGGAATAATTAAGCTCAGATAATTCAAATTAATTAAAATATGAATTACTGGTCAAATTAAGTCCAAATAGCAAAATTGAGAAAATAATGGACAATTAAGCAGAATTCAATAATTAAATTTGGTACAAAAAGCTAAGTGAATAGGAGAAAATAATGATTCATAAGACAACCTTCTTGGTTAAAGAAGGATCCCCCTTGATTATCACTTCTTTTCCTCCTTGGATGAAACATTAAACGTATTGTTAACTCCTTCCAATTGATTCTAACTTCTCCAGGTGTTGCTAACCAAGCCACCCCTAAAATAAGGTCCACTCCTCCTAGTTCAAATAGCAAAAAACCTTCCTGTAGTTCCAGCCCTTCCATCTGCAAAATTAAATCTTTACAAACTCCACTTGTAACTTTTTGATGGCCATCTCCCAAACTAACCTTACAAGGAAGGGTTTTATCTACTTCCAAACCCAGTTCAGCTACTAATTGATTAGAGATAAAGTTGTTACTGCAATCACTATCAATCAAAATCAAAATTTCCTCCCTTGCAACCATCCTTGTAACTTCATTATATTTGTTTGAGTTAACCCTCCTGCAGAAAAAAACATATAACTCCATCTGTTTTTGCTCTTCTTCTCTGACTTCAAATTCTTCTTCCTCTTCATTCTCTCCCAAAATTAACACCCTAAGATTCTTTTCAGGACATTTATGGCCAGGACTATATGGTCCCCCACATTGAAAGCACCTTCTCTCTTCCCTATGCTTGATATATACAAGATATGGTAAATTTTAGAATCCCTTGGTCTTGTTTTCCTCTGAACTAGAACTGCCCACCATAGATTCCAAAGTTACTCCCCCTCCGTCTCTCTTTGTCGTGCACAAGTGATTGGAGCTTCCTTGTTTAGTTCGAGTTCCCTTCTTGGTTTCTACTCGAGAAACTATTCCCTCTTGGCTTGGATATAGATTATTCTTGAACGTTGTCTGTTCTCCAGTCTTGACATCCCTTGAGACTCCTTCCACATCTGTTTCAATCTCCGTTGCTCTCATTAAATCTTTGGGATTATGTGGTCAGATCTAGATTCTAATATTGATATGCAATCTTGCAAAGAAGTATCCCATTAACTGTTCTTTCGTCAAACATTTAAAACATAATAACTACATCACACCCACCAAGAGGAACCGTTTCCCCCTTAAAAGAAACCTTTAAAACATAATAACTACCAATAACTACTGTACTAACCACTCCCCTAAACCATCCAACCTCTCTTAATTGCCCTGTAACTTCTGGTTTGACTTCTTCGTCCTAACATACACCTTTAAAGTCCTATCAAAGTACTAGATCAAATGATGGCTTCCTGTTATGAGGTAGTATGATTTACCCATCTTTGAGCAGACCTTTTGTTGTTTCCCATGTGCTCGAGAACATTATTTCTTCCATGAAGTTTGAAGCATGTTTCCTTGGTATGTGTAGATCTTTTACAGTATGAACAATAGTCTCCACGATTACTTTTTTCAAATGACTTTCCCTAACATTTGTTCTTTCCAGTTGTCATGTGTTGTAGATCTTCCCATCAAGCATGATAACTCTCCGAGTTTTTTCCCTTCTTACCATAAAAAATACTTCTGATAGGGATGATAATTTTTCTCTTTCTAAGATTTGTACCCAGATTAGGTTGTACTCATGATTCAGGCCATGGAGAAATTTAAAGATTCTTCCTCTTTCCACAGCTTCAACATGTGCGGCAGCATCTGTTTTACACATCTTTATTGTTTGGCATTGATCTAATTCAATCCAAAGTCCATTCAGGATTCCGAGATATTCTGATATGGAAAGGGAGTCCTGTTTTTGTGTTAAATATCCTGCTTTCAATGTCATAGCTTGCAACTTAATCCTTTTTTAATGAAAAAGTACTCTGTAAATCATTCCATATCTCTTTGGTAGAAGAATGCAACATATAATTTCGACTTATCTCAGGAATCATGGAATGCCACGTCCAAGTCATAATTAGTGAATCTTCATTGTCCCAAATAGGAAAATAGTGTCGTCTAGTCCTGGCCCTCCTCTATCTTTGTGATCTAGTCTTGAACGTCCCTTGAGAATCCTTCGAGTCACTGTTATCGAACTCGCGAGTTAACTCGTTAACTCGGTCGAGTTTACGAGTTCACATAGTGCTTTTGAGTTAACTTGTAAGCAAACTCGGTTTTGGTGTAGGATCGGTGGAATCGGTGGTAGACTCGATAAACTCGCCTGAAATCGCGAGCCTGGTTATGATTTTGCGAGTTTGGGAAGAAATTTCGAAAACATAAAACAACTTTGTTTTTAGGGCTCACCAGATTAGGTTTTTTGAGCTTTCGTTCAAGAGATTTTGTTACGTATCCCAGTAGGAGACGTAACTAAAACAACCTCTCAATCACTCAAAACAAACAAAAGAATGACAAAATAATGGAATTGAACGAATGGATATCTTTTATTGTTGGTAATGCAACCAAACAATGGAAGAAAAGTGAAATGGAAGTATTGTTCAAAGATTGTAAGTTGAGGCATATTTAAATTTAAGCATCATCTTTTTGGAACTAGGGAAGATTTTGAACCTTGTGCTTCTGTTTCGGATGAAATAAAAAATTTGATGATAAAAATAGTTGTGGAAGCTAAGAATTCTTCATGAAAGAAAAGAAAGTTAAATATCATTGATGAAGATGACGAAGAAAGTGAGAGTGTTGAAGGAGGACATAACGTATTCAGTTTTAAAGGAAAACAAAAAGTTGCTACTACTACCAAGGGGGAAGTTCAAGCAACTATAAATCAAATGATGAAAAAAGGATACAAAGAAGAAGTTGATGCTCAAGTGGCTGAATTCTTTTACCCTAGTGCAATTTCTTTTAATGTAATTAGAAATTCAGCTTTTACAAAGATGTGTGAAATGATTGGTAAGTATGGAGTTGGATACAAACCAACATCTTATCATGATATTAGAGAGAAGCTCTTGAAACAAGCTGTGAAGAAAATAGATGTAGTTCTTGAGGAATATAAGGAGGAGTGGAAGAGAACTGGATGTACAATTATGTTTGATGGTTGGACGGATAGAAAAAGATGTTTTATTTGCAACTTCTTGGTGAATAGTTCTAAAGGATGATTTTTCTTTATTCACTTGACACTTCAGACATTTCAAAAACAGCTGATAAAGTTTTCAAAATGTTGGATGATGTTGTCGAGTTTGTTGGAGAAGAAAATGTTGTTCAAGTTGTCACTGATAATGCTGCAAATTTCAAGGCAGCCGGAGAGTTGTTGGTGCAAAAGAGGGAAAAATTGTATTGGACTCCATGTGCAGCACATTGCATTGATTTGATATTTGAAGATTTTGAAAAAATTTGAAGGTCCATGAATTGACCATTAAGAAGGGAAGAAAGATTACCACTTACATTTATGGAAGATCAATATTGATTTCCTTGTTGAAAAAGTTCACTTAAGGTAGAGACTTGATAAGATCGGGTGTGACTAGATTTGTCACGGCTTATTTAACTCTTGCTTGTTTTCATGTATTGAAGGCATTGTTGTTGACCATGTTTAGCTCTGAGGAATGGAAGACAAGCAAGTTTGGGACTTCACAAGAGGGGAGAAAAGCAGAACATGTGGTATTAGATAGTCGGTGTTGGAAGAATATCTCCACATGCTTGAAAGTTGCTGCCCCTCTTATGGTGGTCTTAAGATTAGTGGACTCAGATGTAAAACCCGCAATGGGTTTCATTTATGAAGAAATGGATTGTGCAAAAGAGAAGATTAGGTCTAACTTTAACAATATCAAAAAGGTAAATTTTCAAACTTTTACTCAATCAATGTTTAATTACTTATGTGTGAAATTATTTCTGATATAGCATAATTGATGTAGTTATGAAGAGGTTCGGAGAATAATTCATGCTCGATGGGATAATCAACTTCATAGGCCTTTGCATGCAACTGCCTATTTTTTGAACCCTCATTTCCACTATGAACCTAACTTTAGATGTGATGATGGTGGAGAGGTGAAAGAAAGATTGTATATTTGCATGAGAAGATTGATACCAGATATGGCAGAAAGAAGAAAAATTAATTTACAAATTGTTGAATTTCATTATGCTAGAGGACTTTTTGGAATGGAAGATGCAAAGGAGTGTAGGAAAGAGTTAAATCCTGAGAAATGGTGGGATATGTTTGGTGATGGAACTCCGGAGTTGAAGAGATTTGTTATTCGAATTCTAAGCTTGAGTTGTAGTTCTTTTGGATGTGAGCGTAATTGGAGCTCATTTGAAATGGTAATTTAAATTATTTTTAATTTATAAATTTTTTTATTATGTTTATATCTTCACTAAAAATATTATATTTCATTTTAGGTTTATACGAAGAGAAAGAATCATTTGCATCAAAAAAAGATGAATGATTTAGTTTATGTGTTGTATAACTCCAAGTTGAAAAGTAGACAAATTTGAAAAATTGTAGTTCTTCCATTTGATGACATTGAATCAGATGATGAATGGATAACTGAAGAGGCAGATGATGTTGTTGAGATTGAACAAGTTGAAGGTGAAAATGATGGTGAAAATGTTCACTTAGATGGAGCAACAACATATCCTACTCTAGATGCTCTTGATCTTGATAACATAACATTTGGGGACAATGAGGATGCACAACATTCATCATAGGAAGAGTTAGATGGGGATGTTGATGCCATTATTATAGGATTAGACATAGAGACTTTGACATTTCAATTTATGTTTTACAATATTTCTATGAACTTATGTATTTGAATTTATATAATTTTGTTATCTTATTTGAGTTAGGAATGTTATTTATATATTTTTTTCATGCAAAGTACATTCTTACGAGTTTACGAGTCGAGTTTATTGGACTCTCACGAGTTTACGTAAACTCTTGAGTTTGACAATCTTGCTTCGAATGTACTAGATCCATTTTAAGAAATTCCGACCATCCTATTGATAGGCACCCACCACATTTGGAACATCATTAGGACCCAAAGGAATAATTTTTACCTCAGACATCCCTTGGAACACAATCAGGTTTCTCCGGTGGCCCTATTCGAGACGACGACGACGTGTGGGCTACACTGGAAAAAGAAGCAGAACTTAAAACTCAGATCTACTCAAATCTGGGCTAGGAGGCTCCGGGGACCTATGGAATGGACTCAAGAGGCTCCGACGACCCTTTCTGTGATGGTGGCGGTGAGTGGGTCTCGCCGGAGCTAAGCGTGTGGGCTACATGCGTCGGCAATAGTGGTGGCGTGTGGCGGCGTCTTTTCCAAAGCGATTTCGAGCGTTGTGTGCGTCGGAGTTGGGCACACCTTTCTACCCTATCAACAAACCCAATCGACTATGGCGGCAGTAGTAATGGGCAGACAACGGCGACGGTGGCTACTGATGAGCGGAACGGAGCTCCCAAGATTAGGAGTTCTGATACCATCTTGAAAAAGAAAATGAATTTTATTATTTTCATTCATGTCTGTTACATTCTCCTTACCTCTATTTGTAATAATCTAATCTTCTAGAAAAGGAAAATAAGTAAACAACATACTTAAAAATAAACTAGAAGATTATATAGATATTTTCTATGATTAGAAAGATTTTATAAATATTTTCTTTAATTAGGAAGATTTTCCTCTAATTACAACACCCTTTTCCCACTCTCATCAAAAAGAGACTAAATGAAAGTGAATCCATTCGGTAGATAGTTGGAGCCAATTGATTATATTTGGGGTTTAAGGGCACTTGTATGTTCAACTAATAGTGACTTGATTGCAGGGTCGTCTTAAAATTGGAGACTTTGGTTGGTCTGTTCAGTCTAAAAGCAAAAGACATACCATGTGTGGCACATTGGATTATTTAGCACCAGAAATGGTTGAAAATAAAGCTCATGACTCTGCTGTTGATAACTGGACTCTTGGTATCCTTTGTTATGAGTTCCTCTTTGGTGCCCCTCCATTTGAGGCTGAGAGTCAAGCTGATACCTTCAAAAGGTACAAAACTTCTTGGGCTATATGTTTATTTAAAGTAGACGCTGTTCTTTCATTGTGTATTTAATGTATTTAGCTTTGTGTAGGATAATGAAGGTTGACCTAAGCTTCCCTTCCAACCCTTCTGTTTCTTTAGATGCCAAAAGTCTGATTAGCCGGGTAAGTTAACATCCAGTATTGATATCTTGGCCAAAGTAAATTCTTTCAGTGAACAAATTAGTCGTCTTTCTGACAGCAATCTATAAAATAATGTAGCTTCTGGTGAAGGACTCCTCACGAAGGCTCTCTCTTCAGAAGATAATGGAACATCCTTGGATAGTCAAGAATGCAGATTTTTCGGGTATTTGCTTGTAATACCGACTTAATTACTCATTTAACTGGGAACGAGGGATTAAAACTGAATTCTGTATGTGATGTAAAATGCAAGCAATGTGAGTGTTTTGTAGTGTACTATCATCAGCTTGAATGACTCATTATCTTCGCCGTGAGGTTAGGAGCATTAGGATTGTGTATATGCTGATCTAAACCAGGCATGACGAAGATTTATTTTTGTCAATACTGAATGTCACCCCTCAGATTTAACGATTTCTCTTTGATGAGTTAGGCCTACGTTGAAATTTGGATAATTAATATTGATATTTTGTCTTTCTTTTTCGTAAGTTTTAAATGGAAAAATGATTTTATAATATGAAATCAGTTACCAAATTAGGATATTTGCTGTTCATGATGAAATTTGGATTCTAATTCCAGCGGAGCTGCTTCAAAGGGTGCTGCAATTCTAA