Gene Details:

Gene ID Chr. No. Start Position End Position Function View on
Vu_30553 LG8 38261373 38271897 PREDICTED: 3-phosphoinositide-dependent protein kinase 2
Map

Annotations  
category   relationship type   keyword
Biological Process   involved in   protein autophosphorylation, protein autophosphorylation, protein phosphorylation, protein autophosphorylation, protein autophosphorylation, positive regulation of protein kinase activity, positive regulation of protein kinase activity, intracellular signal transduction, protein autophosphorylation, protein phosphorylation, peptidyl-serine phosphorylation, peptidyl-serine phosphorylation, positive regulation of protein kinase activity, positive regulation of protein kinase activity, protein autophosphorylation, positive regulation of protein kinase activity, peptidyl-serine phosphorylation, protein phosphorylation
Cellular Component   located in   nucleus, plasma membrane, nucleus
Molecular Function   enables   protein binding, phosphatidic acid binding, protein kinase activity, protein binding, protein binding, protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein kinase activity, ATP binding, protein binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, ATP binding, protein binding, protein serine/threonine kinase activity, protein binding, protein binding, protein binding, phosphatidic acid binding, kinase activity, protein kinase activity, protein serine/threonine kinase activity, protein binding, 3-phosphoinositide-dependent protein kinase activity, protein binding, protein serine/threonine kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, protein binding, protein binding, phosphatidylinositol binding, protein binding, protein kinase activity, 3-phosphoinositide-dependent protein kinase activity, protein binding, protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity, protein binding, protein binding, protein binding
Pathway   B 09132 Signal transduction   C 04011 MAPK signaling pathway - yeast [PATH:ko04011]
SNP Position Effect Amino acid change
A/C 38261444 3_prime_UTR_variant
T/A 38261667 3_prime_UTR_variant
G/A 38261942 downstream_gene_variant
T/C 38261951 downstream_gene_variant
G/C 38262135 downstream_gene_variant
A/T 38262271 missense_variant p.Val430Glu
A/C 38262440 downstream_gene_variant
A/T 38262617 downstream_gene_variant
T/G 38262649 downstream_gene_variant
T/G 38262659 downstream_gene_variant
G/A 38262701 downstream_gene_variant
A/T 38262899 downstream_gene_variant
G/A 38263185 downstream_gene_variant
C/G 38263202 downstream_gene_variant
A/G 38263269 downstream_gene_variant
G/C 38263325 missense_variant p.Gln325Glu
T/A 38263331 missense_variant p.Arg323Trp
T/C,* 38263530 downstream_gene_variant
G/A 38263647 downstream_gene_variant
C/G 38264232 downstream_gene_variant
A/T 38264454 downstream_gene_variant
A/T 38264795 downstream_gene_variant
T/C 38264908 downstream_gene_variant
T/A 38264941 downstream_gene_variant
A/T 38264995 downstream_gene_variant
G/A 38265260 missense_variant p.Leu203Phe
A/G 38265380 intron_variant
A/T 38265417 splice_region_variant&intron_variant
A/T 38265587 intron_variant
T/C 38265589 intron_variant
G/C 38265594 intron_variant
A/G 38265600 intron_variant
A/C 38265647 intron_variant
A/G 38265868 intron_variant
T/G 38265888 intron_variant
C/T 38266238 intron_variant
G/A 38266244 intron_variant
G/A 38266246 intron_variant
C/T 38266255 intron_variant
G/A 38266331 intron_variant
T/C 38266332 intron_variant
G/A 38266360 intron_variant
C/T 38266543 intron_variant
G/T 38266571 intron_variant
C/G 38266581 intron_variant
G/A 38266935 intron_variant
A/T 38266994 intron_variant
T/C 38267013 intron_variant
G/A 38267154 intron_variant
A/C 38267523 intron_variant
G/T 38267746 intron_variant
G/A 38267747 intron_variant
T/A 38267918 intron_variant
C/A 38267928 intron_variant
C/T 38267962 intron_variant
A/G 38267969 intron_variant
T/G 38268049 intron_variant
C/A 38268107 intron_variant
G/A 38268349 intron_variant
T/G 38268523 intron_variant
C/A 38268527 intron_variant
T/A 38268783 intron_variant
A/T 38268784 intron_variant
C/A 38268920 intron_variant
A/G 38269178 intron_variant
A/C 38269346 intron_variant
A/G 38269410 intron_variant
T/A 38269794 missense_variant p.Ile136Leu
A/T 38269798 missense_variant p.Asp134Glu
T/C 38269826 missense_variant p.Glu125Gly
T/A 38269840 splice_acceptor_variant&intron_variant
A/T 38269863 intron_variant
T/C 38269961 intron_variant
C/A 38269991 intron_variant
A/G 38269992 intron_variant
T/A 38269997 splice_region_variant&intron_variant
C/A 38270177 missense_variant p.Arg63Met
G/A 38270370 intron_variant
C/G 38270563 intron_variant
T/C 38270806 intron_variant
A/G 38270816 intron_variant
G/T 38270894 intron_variant
T/A 38270909 intron_variant
A/C 38271079 intron_variant
C/G 38271086 intron_variant
T/A 38271088 intron_variant
A/G 38271218 intron_variant
C/T 38271353 missense_variant p.Gly23Ser
A/G 38271360 synonymous_variant p.Ser20Ser
G/A 38271386 synonymous_variant p.Leu12Leu
T/A 38271389 stop_gained p.Lys11*
G/A 38271442 5_prime_UTR_premature_start_codon_gain_variant
A/G 38271453 5_prime_UTR_variant
A/T 38271800 5_prime_UTR_variant
A/C 38271847 5_prime_UTR_premature_start_codon_gain_variant

View accession wise SNPs


Sequence Details:

Protein Sequence:
>Vu_30553.1
MLEMEKDFDSKLKIQGNTSSSNGGGNVQRSKSFAFRAPQENYTIQDFELGKIYGVGSYSKVVRAKKKDTGTVYALKIMDKKFITKENKTAYVKLERIVLDQLDHPGIVRLYFTFQDSFSLYMALESCEGGELFDQITRKGRLTEDEARFYAAEVVDALQYIHSLGVIHRDIKPENLLLTADGHIKIADFGSVKPMQDSQITVLPNAASDDKACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIVARELRFPDYFSDEARELIDRLLDLEPSRRPGAGPDGYAILKAHPFFKGVDWKNLRAQIPPKLAPEPGTQSPAADDVHDSSWSPSHIGDCPSASVRQPDGATSSDGSSHITRLASIDSFDSKWQQFLDPGESVLMISMVKKLQKLTSKKVQLILTNKPKLIYVDPSKLIVKGNIIWSDNPNDLSIQVTTASNFKICTPKKVMSFEDAKQRAWQWKKAIEGLQNR*


CDS Sequence:
>Vu_30553.1
ATGTTGGAAATGGAGAAGGATTTTGATTCGAAGCTGAAGATTCAGGGGAATACCTCATCTTCCAATGGTGGAGGCAATGTCCAGAGATCCAAGAGCTTTGCTTTTAGGGCTCCTCAGGAGAATTACACTATCCAGGACTTTGAATTGGGCAAGATCTATGGTGTTGGTTCTTATTCTAAGGTTGTGAGGGCAAAGAAGAAGGACACAGGAACTGTCTATGCATTGAAGATCATGGATAAAAAGTTTATAACTAAGGAGAACAAAACAGCTTATGTGAAATTGGAACGCATTGTGCTAGATCAATTGGATCATCCAGGCATTGTGCGGTTATATTTCACATTTCAAGATTCATTTTCTCTATACATGGCACTTGAATCCTGCGAAGGTGGAGAACTTTTTGATCAAATAACCAGGAAAGGTCGTCTAACTGAGGATGAGGCACGGTTCTATGCAGCTGAAGTTGTTGATGCTCTTCAATACATACATAGTTTGGGAGTCATACATCGTGATATTAAGCCAGAGAACTTGTTACTCACAGCTGACGGACACATTAAAATAGCAGATTTTGGGAGTGTGAAGCCTATGCAGGATAGTCAAATCACTGTCCTTCCAAATGCAGCGTCTGATGACAAAGCCTGCACTTTTGTGGGAACAGCTGCTTATGTTCCTCCAGAGGTTCTTAATTCCTCTCCAGCAACTTTTGGCAATGACCTATGGGCACTTGGCTGCACATTATACCAAATGCTTTCTGGAACTTCCCCTTTTAAAGACGCAAGTGAATGGCTTATTTTTCAAAGAATTGTAGCAAGGGAACTTAGATTTCCAGATTACTTTTCTGATGAAGCAAGAGAGCTCATTGACCGTCTGTTGGATTTGGAACCCAGCAGAAGACCAGGTGCTGGACCTGATGGTTATGCTATTTTGAAAGCACACCCATTTTTCAAGGGGGTTGACTGGAAGAACTTGAGGGCACAAATTCCTCCAAAACTTGCTCCGGAACCTGGGACTCAGTCACCTGCAGCTGATGATGTTCATGATTCGTCATGGAGTCCTTCTCACATTGGGGATTGTCCCTCGGCTTCAGTTAGACAACCTGATGGTGCTACATCTTCTGATGGGTCTAGTCACATAACTAGGCTAGCTTCAATTGATTCCTTTGATTCAAAATGGCAACAGTTTTTGGATCCTGGGGAATCTGTTCTTATGATCTCTATGGTGAAGAAATTACAAAAACTAACAAGCAAGAAGGTGCAGCTCATCCTCACCAACAAACCAAAGTTGATCTATGTGGACCCATCAAAGCTAATTGTGAAGGGAAATATAATATGGTCTGATAATCCAAATGATCTAAGCATCCAAGTGACTACTGCATCAAATTTCAAGATTTGCACACCTAAAAAGGTAATGTCGTTTGAAGATGCTAAGCAAAGAGCATGGCAGTGGAAGAAGGCAATTGAAGGACTTCAAAACCGGTGA


Promoter Sequence:
>Vu_30553::LG8:38271897-38273897(-)
TTAAAAATTAAAGACTATACCACAAAAGTCTTAACTTAAAATTTAAAGCACAACAATTATGTCCGGTATAGAATTTTTGTTAGAGTAAATTTATCTTTTTTTTTAGTTATTTTAAGGTTTTGTGTTGTATTTGTGGTAGCATGTAACTAAAAAAAGTTTTAGATGAATATTTTTTTGTAGTAATCATTTTTATATAATCGATTTGAGTTTTTTTTTATAAGTAAAGTATATTAGGAGAGTTAGAACCTTTGGAACATAGTTGAAAAACCTAGTCTAGATACGGTAAACTAGTTTGTATATTTTATTGAATGAATTAATTTTGAAAAAAAAATTATAATTCGTTGTCTTTGTGAGTTGATCAGGGATAAGTTTGATTTAAAATGTTGAATTGTTTTGGAGTGATGGGTGGATTAAAATTTTGAATGCTGAATGAAAAAGGGATGTATCAAATAATTTTGGGTTAAGTGAGTTTTGAACGATGATAATATACTACTTTTATCAATTTGTTATGTTTAAAGATGTTCTTTTTAACTATATGGTTGTATTTGTAACACGAGAAAGAAGTAAAACTCTTCAAATAAACAAATTGATGATATGATATATTTATTTAATTTCTAAAAGTATGTAAACTCTTTTAGGCAACCCAATCAAGCAAAAATAAATTTTCTCAGGTCATTATATTTGTTTGAGTCAATTCTGAGTAAGTGGGTATTGTGAAAAAGAGTTTCAGGAATTTGGGTAATTGGACGAGTAAAATACTTTTTGAGCAAAAATATTTTAGTGAGATTTCAAATAGCTCACAATGGTTAGGTTGATAGGAAAATTTAATCTCGATGGACAAATTTGTGTGATTTTTATTTCTATTATCCGGTCACATGACAACTCAGTTCTTTCAATGTTTGAAAATAAATTAATGAAAATTCAATAAATTTAGAAGAAACTAGTCATTGAAATAAGTCATGACTCATTGAATGAGTACACCTTTAAAGGTGTATTATTAAATATTGGAAATCTAAGTTAGAATCTAAATATCACATTTAACTTGAGAGTGATATAAACTCTTTATGTGATTAGACTACGTCTCATTAATGTTTTATATCATTAGTAAACCTCTTTTTTTTTATATACACTTAACATTAAATGAGTTTATGAATAAACTTTTATACTTGTGAAATGACAAGACCATGAGATAAAATAATAATAAAATTAGACAAATAAAAAAAATTATTATATATATATATATATATATATATATATATATAATGTAACGTGGTTAAATTAAAATATACATCATAATATATTTTTTAAATTTAAATAGATAATTAAATAAAAAAACATGAAAATATGTCGATCCGTGTTAAGTACATTTTTAATACTTATTCAAAGACTGATAAAGTTAAATTAATTCATTTACTTCATGAATTAAGACAGGTTTAATCTAACACCGAAATTCTATTAATAATATAAAAAATAAGGAATTGTTTTTTAAAACGTTACTCGGAATTGCTTCTCATAAAACTGACAGGATGTCTGCTATGGTCTTAAAGGATCATTTAAAAGTGCAACATAAGAGCAGCGAAACATGACTATATCCGTAGTCTCATTAAAATTATTTACATATTTAATAATACCTTTTTTTATTTATTATTAAAAATTAAATAAGATGACACGTCTCTTTTCCTATCTCTCTTCGATCAAGCCAGATAAAACAGTTTATTTTTCCCACTTATTTTATGAAATATTCATAATTTTTGCAACGCTATCGAAATATAATGGTAGATTATTTATAATAAAGGCTCTGTTTGTAATTGTATTTTTTATTGAGAAGATTTGAATAAATACGTAAGATGTGCAGTCAAAAGGGTCAAAGAAAGGAATAAAAAAAATGTAATCTAATCCAAAGCAATGTTGGAAGTAAGAGAGGATGTGTGTGTCCATTGGACTAATGAATTTGGAAACAGGACAGTGACAGAAAAGCATGAAATTGCACAAAAGCTTGT


Gene Sequence:
>Vu_30553(-)
AATGATATGCATTATTTATGCAAACACTCCAAAACACCACACCCTCCTTTTCTTTACCTTCTCTTCCCATCCCATTCCATGACAGGTGTTTGCATTGTTCCTGAATTAGGCATAATAGCCACAAAGAGAGAGAGAAAGAAGGCATGAGAAAATGAACGATCTCCATCATCATTCCTTCCCCATGTGATGTGCCACCCCTCTCTCTAGGGTTTTCAATTTCGGTTTCAATCAACCAACCCCAAACCTCAAAGCTCACACCTTTCCCATCCATTCGCACAATTCCCTTCGCCCTTTTCCTTTTCTCACAAAAGGGTCTCCGGGGCTTCGCCTCTCTTTGACCGTTCCGGGCTCGCCTCCCCAGGCCTCTAGAAAGACAAACATAACTGCTTTTCTAGAGAGAGACAGTCTCCATGCCAACGTAGAGTGGAGCTTCTCTTGTTTTTTTTTTCTTCTCCCTGCTGTTGGCGGTGACCGAGCAATGTTGGAAATGGAGAAGGATTTTGATTCGAAGCTGAAGATTCAGGGGAATACCTCATCTTCCAATGGTGGAGGCAATGTCCAGAGATCCAAGAGCTTTGCTTTTAGGGCTCCTCAGGAGAATTACACTATCCAGGACTTTGAATTGGGCAAGATCTATGGTGTTGGTTCTTATTCTAAGGTCTCATACCTGGACTTCTAATGGTTTTTTTAGTGGGTTGACGATGTTGGTTTACTTTTTTTTTTCTTTTGTATGTGTGCAATGTTTTGATGGATAATAGTAATACATGAATCCTGTAAATGATGTTGCCTTTGTAGTTCTGTTAGATAATACGTGTTGGTTGCCTTGGATAATCATTGATGCTTATTAAGATGCAGAGATCATTGGGCAATATTGTCATCGTTGTTGCTATGTATTATTATGCAGCACCATTTGGTGTATTATCTTCATTTGGGAATTTTGGTTGGCTGGGGGATTCTTTTTATGCTATGACATTAATGTTTGCTAAAAATTTTATGAAGGCTGCTTGTACCCCCACACGTTCCTATTCTCTCTGAAGCCGCTCTCTTCATTTTACAGAATAGGAAAATACTCAACGTTTTTTCTAAGCTGTATTGTGAACTAAATTCAAAGCTTCAGATTTGGAAATCAAGCTGGTTTTTTGTTTAAACAAATTATTCCTGTCGATTATCTCTGAATTAATTATGGAGAATATATTGAATTACTGAGCTGGAAGTAAAAGAAATTATAGGCTGTAGAAAGTGAAGCGAACTGAAGAACTGATTGGCTTGGTTTTGTGGGGTTTACACATGAATCCAGTAGTGCAGAAAACAGCATTATATTATTCCCCCTTTGAGTGTATTATTTTGTTGCCTTATGCCAGTAGTAGTGTGTACTTATTAAACTACGTTGATATCAAATAGGAGTATGTGACATCTTACAAGAAAACATATGTTTCCTTTTCTCTATTTGCTTGCGATATCATAGATTGCCGATGCTTCTGCCTTTCCAGCTCCCTTAACTGCACGCTCCGTCTCTTACGTGATTTACGATTTGGTTTCTTCTTTATTCAACTGTTTGGATTAGCTGTGCACAAAAAATTATACCAATTGATGGAAATATCTATAATTTCTACAATTTTGCAACAATTTTTTTCTTCTGTTATACGGTGAGCTGTTGTTTGATTGAATTTATTTCCCCTTGTAAATTACCAACTAATATATTTCTTATCAAAGGTTGTGAGGGCAAAGAAGAAGGACACAGGAACTGTCTATGCATTGAAGATCATGGATAAAAAGTTTATAACTAAGGAGAACAAAACAGCTTATGTGAAATTGGAACGCATTGTGCTAGATCAATTGGATCATCCAGGCATTGTGCGGTTATATTTCACATTTCAAGATTCATTTTCTCTATGTAAGTATTTCTGGGTGTATTTTATCTTAAACACTTGCTTTTACCGTGGCTTACTCGTCTATGTTATCTTCTCAAGTCTTCCTTTTACACCCTTGCTTGCCAAGTTGGTTTATATTATTTTGATGTTATCTTTTTTCCCTTCTGTTCCTTTTTACATCGGTGAAGACATGGCACTTGAATCCTGCGAAGGTGGAGAACTTTTTGATCAAATAACCAGGGTAAGCTAACGTGAAACTTAAAGGCACATGTTCCCTGTGCTGGGGTATTAATAATTTGTTCGTAAAAATCTTACATAACTTGTGCTGAAGGTGCTAGTCCTGCAGGACCCAAGTTTAGTCCTACATTAGGCCTTAGTATTAAACATTAAAACAATGACGTTTGCTATGCTCTTATGATTGTCTAAAGAGAGTAAGTTAAGCATAATTTCTTTTAACATGGGGTTTTCTAAGATTTGCATAAACTTTTTTCATTAATTCCGTGTATACACATAAGTGAACATTTTGATACGTAGGAATTTACACTTCACTTCTCAGTTTCTTGCGATAACACTCATCTTAGTTTTGCTTAAATCTTCTGTTTACTCCATTTTACCTTATTCATCAATCCCCATTCTAAATCGAGAGAATACTCCTTTGAACATTAAAAATGAACCATATTTAATGCTTGGAATATTAGATGTCTTATCTTTAGATTGAGATCTATAACCATGCAGTGTGGTGTCGTGGTCAATCCCCCTTTTTCTTTGTAGTTTTGTTTCACTGGGTACATTTGTCATTTAATTCAGAGAGTACTTTTAATTTTATTTCAATATTTTACCATTCATCTTTCCTTTGAGTTGTCAATCTTTTTTCAGTTTAATATCTTCAATCTTCTTTAAAAAGTGTGAATATGTGAATACTTAAACATTGATTGAACTTGAGAATTCTGCAGTCTGGGTCAAGATACGGCCCCCTTTCCCTTTAATTAGGTAGAAGCTTCACATCTGAATCCATAGGAGTATTATTTGACTTACAATCAAGCACCCTTGGCTCTTTTAAAGTGTTAAGGTTATATTTTCTAGAAGAAATCACAATACTTGCCTATGATTGACCCTCTTCAATTCCAAGAAAATAATGTAATAGCCTCAATCATTGGTTCAAAGGTGCTTGAATAAGTGTTGCTTTAGGTCCTTAATCTCGATCATCACATGTAATGACAATATCATCTACGTATACCACAATAAATTAGTTTATTCAAAGATGAACATCTAGAGAATATACAATGACCAATCTCATTTCAAACCATGTAAACTTTTGAATAATTTTGCTAAACTTCCTTAACCAAGCTTAAGGTGATTGCTTTAGACTGTACGCCTATTTTTTTAACCTACTAAACAAATGCCCATCAGCCCTGAGCAACTAAGCCAAGTGGTTGCTCTCTGTAGATCTATTCTAAGTTACTGTGTAAAATGCAATTTTAATATTGAGCTACACAAAGGCCTATGACTCATTTCACCCGTTGACAATAATAAGTGAATAGGCATCATTTTAGCATTTGGTGACAAGGTATCATTGTAGTTTAAACCATAAAGTTGAGTGCATCCTATTGTCACCATATGGGTTTTCAATCGATTTACCTATTCATCAAGGTCCCCAAAGGCCAACGACTTGTTGCACCTAGAGACAAGAATAAGTGAATAGACGTCCATTTAACATTTGGAGACAAGGTAGCCAAGCCATACATTTGAGTGTATCCATTTGTCACCATTTAATCTTTCAATTGACCCACCCCTCTGTTTGGGTTCATTTTATTAGCAAAGACCCACCAACAACCAATTGTAGATTTTTCGAGTGGATGGGATTGAACTCCAAAGTAGCCATCACTTCCAGCATTTCCTATCATCATCATCTAGAATGGGACAATGCTTCCTAGACAGTCTTTTGAGATGTAGCAAATAGAATGAGACAATTGATGAAAAAAATTTCTAAATAGGATGAGAACTAACAATTGATGGTTTACCCAAATGTCAATAGACATGTTAATAGAAGGGCTAGGTTTAGGTGGGACCTAAGCGGTAGAAAAATGCTAGAGTGGGGGTTGAATCACAATCAATAGGAAAAATCTCAAGAGCATGGAGACCTCAACTTTGCAACTAAGGGTCATCTTGGGATTTGTGGAGAACTGAGTAGAGATGGGCAACTAAAAGTTAGGAATAAGTGAAAGTGGAATTGAGGAATCTGTTACAGCTACAGATGCAAAGAAAGGCATCAAAGGACCCCGTACGAAGACCATAAAATGATGCATAGATGTAGAAAATCCTTGATACCCATTTTGTACTTTGAAATGCCAATCAATGTTTATTTTATTGCCATGGCAAGCAAGTAGGAGTGGGATCATAAACAAAACAAGTGAAACCAAACACTTGGATGGGGAACAACATAAAGGGGTTCTTGGGAAGCAAAAGAGAGTAATAATTCTCATCACTAAGATTGATGATGGCATACAAGTTATTGAATTACCGGTGATGAGAACAGCACCCTCAAAGTTAATGCACTTATCAATGGTGTCTAAGTCATCAATAATATGACAATACTTATGTTCTTCACACACAATTTTTGTTATGGTGATCGAGAGCTACTAAATTGATCTGTGATGCCGTAGGATGGATTTGTACAATGTTTATGTTCAGTCACACCATTTACAACACCAATTGTTTGTCTAAATTGATTCCTTATCTTTGAACAAAAATCTTGAAATGACATCTTGTAATTCATATAACGGATCTCAATTTGTGGGATAAGGCTTTGTTGTTGTTGGATCTTTCGTTAAAAGTAAGAATGTGCATCTTTTGAGGTTATCAATGAATGTGACATTTGTATCCAAAATTAGAAGGCACGTGACTAGGACCTAACCATCAGATTCTTGACACTAGTTTAAAAGATTGTCCTAATATTTTTACCAAGCTGACATGACTCGCTCCAAGGACTTTGAATGTGAAAGATGGACCACTTACTTTAACTTATTCAAACTTGGATGACCTATATTATCTACAAAACACAGTGGATGAAGGAGGTTATAGAGACTCCATACTTTAGATATTTCTCCAACCATCTGTCTCATGTTCCAATCTTGTATGAAGAAAACGTCTAGTTTTAATGTTACAGAACAATCGAGAGAACAGTTAGTTGATTGATTGAAATCAAATTGAAGGGGTAACTTAGTACAACTAAGAAGGAATTAGAGATAACTTTTGAAAAGACAAAGCTTAACCAATACCAGCTATCTTTCCTCCAAAACAATCAATGAGGGTGATGTGGTGAGTTGATTCAGGTGAGAGGTTAGAAATAAGAGAGATTACTAACATGATTAGAAGTACCAAAATAAAAATTCATTATCTCTACAAATGCAAGGTGAGATAGGTATATAGTAGGATTACTGCGTGAGTAATAGTTGCTAAAGAGGAATCCAGTTGGGATACCTTGATTTGAAGACACTTATGTTCTCTGGGAGAAAAATGATAAATTCCTTTAGAATGTCTTCTGCCATAGCCACTACCCCTACAACTACAACCTCTTCACTTGGTCAAAGTTGTAAGACTCTCTACCAAGATGAGCAAGTGAGAAACTATGAACACAAAAAGGGAAACCAAAAATGTAATGCCAATCACAACACCTAGATAGCAAATAAAGACCACGAGTTAAACATGGATGGCTTGAAGTTTTTGTGACAACACACAAAAAAAGGAAACTGAAAAGGAATATAAGGCTTTGAGGCATTGCACACCAAGTGACCAAATCCCTAACTGGAAACTGAGGAATGGCTTACCAAAGAGCTTTGCTACCAATTTGAGATGGTAAAAATAAGTCCGTCGTGTATATTAGTAAATGATTGATACACTTGTAAACATAAGGGTTGAATCAATTCCCAAAGTTTAGAAGTTGTAATTAGTAAAGCAAGGAAACTAATGAAACTAAGGAAATAAAGAAGAGAAGGACTTATATTTTCTTTAGATATTATCTCTAGCACAATATCTTAACATGAAAAAAATGCTTTTCAGCCAAGAGCTTTAGTTGCTGCATTTTTTATTATAAGATTTTCTTATTCCAAAATAGGCTATTCATACAAGCACTTATATCACTAAGAGGTTTAAATGGGATAGATTGTATTATCAATAAATCACATTAGAACATCTGGTTTCAAAGTACGGATCCACACTACTTACTAGAACAATGATTCCCAAAACGATGGCAGTACTAAAATAGCATTTGTCCATGCTCTACTAGTATTACCCAATGCCCCCTCTTACCTCCAAACAAAATTACCCATGTACGCCCATATTTTCTTTATCATTGTTCATCAGCTGTGTCAGTGGCTTACTAAAGTATTTGTACTCGGTACTATTTTGGATATGGACGTTGTTAATTTGTCTGCTAGTATTTTTGTGCATGCTTGTTACTACATGATATCTACTAGCAACCTTTCTTATTTCTTTGTGCAGAAAGGTCGTCTAACTGAGGATGAGGCACGGTTCTATGCAGCTGAAGTTGTTGATGCTCTTCAATACATACATAGTTTGGGAGTCATACATCGTGATATTAAGGTAGTTCTGTATCATGATTATACTGCATCATTGCTGTATTTGGCTATTTGAATATTGAATTTCTTCAACTGCAGCCAGAGAACTTGTTACTCACAGCTGACGGACACATTAAAATAGCAGATTTTGGGAGTGTGAAGCCTATGCAGGATAGTCAAATCACTGTCCTTCCAAATGCAGCGTCTGGTAAAATAGGCGCAATGTGGATGCTGCTTTTTATAAGTTTCTCTTATATTGTATTTATATTTATTTATATTTTTTAAATTTCTAGATGACAAAGCCTGCACTTTTGTGGGAACAGCTGCTTATGTTCCTCCAGAGGTTCTTAATTCCTCTCCAGCAACTTTTGGGTAGGCATTAAATTGTCAAGTAATGCAGATGAATTCTATGTTGATAGGAGTTACTTTTGAATATAGTCATTTACTTTTATCCTAGAAAATATTATTGGTTGTGCCAGTTTTTCATGCATGTACATTTTTCACTTCAATTTTTTACTTTTTTTTTGTCTTTTTTTCTGAAAATCAAGAATTAATTTTTTACAACTCACATTTTACGTTTGTTCATGCACTGAGTTTCTTTATTTTGCTTTATGTTTCATACCAGGTTCCCATATAATAACTTTTATTTTTTGTTTTTCTTCCCTCAATATATCACAACAGCAATGACCTATGGGCACTTGGCTGCACATTATACCAAATGCTTTCTGGAACTTCCCCTTTTAAAGACGCAAGTGAATGGCTTATTTTTCAAAGAATTGTAGCAAGGGAACTTAGATTTCCAGATTACTTTTCTGATGAAGCAAGAGAGCTCATTGACCGTCTGTTGGTTAGTCTTTTAACTGTGCACATAGAAATCTTAGCATCACATAATTTTTATACGTTTCTAATTGCTTAAAAAAATTCTCTTTTCTATTTTTGTCAATTAGATACCAACTCAATATATACATATTAAGATGTTTCATTTCTGGCCTTCTTGAAGGACAATGTTTTGAGATGGGGTGAATTTTGCATGTATTTTTTGTTAATTCGGTAGTTGCAATGGTCAATTTCATTCTTCTAACCAGTACCCATTGGTTTTTATTGGTTGTCAGGTTTAGAACATTTTAATAGTTTTATTCACATTCATTTATTCCAAGGTACTTCTGATACCTTGCAAATATATAGCCTTTAAGAAAGGCTATGCTGCCTCTGAGGGGGTGGGATGATGAGTCAAATTGGTGCATGGTGTGCCCTTTTTAATAAATAGTATAATAATAACCAGAAGCAAGAAGGTGTAGTTGTAGACTATAAGATAACACATAATGGGTGCTTTTGATGGATATTTGAAGGATAAGTGGACAACACAAGCAGAAGTTAAGAAACTGAGCCTCAACACTACTTTTTGTTTTGTCTATTTTATGGACGTGGTTTATGCTAAACAATTTCAAAGGATGGAGTGGAAATTTGTGCTCGGTTAAAAGCCCAATTGGGCTTCCTGGCTGTTCTCAGTTGACAGTTGTGGGATTTTGGCCAAATTGATGGGTATTTTCTATTTTTGGATCATTATTGAAGGACAAAAAATTGTCACCATTACGTTATGTCATTTTGTTTTGTTCCGTCCAACAAGTCCAACTTATTTTAAAGGCCACATGAAAGCAGTATTGTAATGCTGTTTAGTCACTCAGGTTTTAGCAAGTCAAGCACCTTTTAGGTTTTTATGAGGGCTATTACGTAAATATATTACACAGACCCACGATTATTTTTTCCAGAAGAATATTATACATGAATGAATATTGAAAAGACGTCATGTTATTTTATAAGTGCGTAAAACATGAAAAAACAGTACGTTAATTGTAATACTAAAGATTATCATGTAATGGTATATATATATATATATATGTATATATATATATATATATATGTGTATGATAATATGACAACTTTTTTAGCATGCTTTAAGTTGCATGCCATTGGGTTTTAATTATGGAGTTTTAATTTGAAATCAATGTTATTATGATGCAGGATTTGGAACCCAGCAGAAGACCAGGTGCTGGACCTGATGGTTATGCTATTTTGAAAGCACACCCATTTTTCAAGGGGGTTGACTGGAAGAACTTGAGGGCACAAATTCCTCCAAAACTTGCTCCGGAACCTGGGGTGTGATTACCATTGCTTTGCTCTCTGAAATGTTATTTATCGAGAATAAGAAAAGGAACCTTCATTTCTTGTCCTCCTCTACCTGTTGATGAACATGAAGTTTCTGACACTGACATAACTTTAACTTGCAGACTCAGTCACCTGCAGCTGATGATGTTCATGATTCGTCATGGAGTCCTTCTCACATTGGGGATTGTCCCTCGGCTTCAGTTAGACAACCTGATGGTGCTACATCTTCTGATGGGTCTAGTCACATAACTAGGCTAGCTTCAATTGATTCCTTTGATTCAAAATGGTATGTTGAAACCTTTTCTTGTTGAAGCGTTTTTTCTTTTAATCATAGTCTAGTGAAGGGGAATTGATATGATGTGTTCACTTTAATATTAATGGTTTTATGAAGATTCTTAACTATTTATAAATCATGTCACCTTAAAAGAGGCTCAAATGTTAGTATAATTTTCAAATTAAATAAAACGTTCAAATATGGCCAAAAGAATATTTTGAAGCTATATCCTCAACGTTTTAATATTTTTACCACATGGTGAATGCTATATTTTGTTTTATTTTATTTTCATACTTTACAGCTTTTCACGCAAAGAACACTGTACATTTATTTATCTTTTTGGAATCACAACTTGGGGACAAAAAATAACAGCTACGTTGAGGTCTATTTCATCTATTAATATTAATTTACATAGATGTTTGGTTATATGTTCTCCAATGTCCTTTCGCTGGTAGTGTTTAATTAAAAAAATTGCATTCTCAGAGAGATACAAATCTATTCCCTTTCAAGCAGAAACTTAACGTTTAGAAAAATAAAATAAAGAAAAGCTCTTGCGTACAGTGCCTGAATTTCAAGATTACCTGGCTTTTCAAACTGTCAATTTATGCTCATATTACAGGCAACAGTTTTTGGATCCTGGGGAATCTGTTCTTATGATCTCTATGGTGAAGAAATTACAAAAACTAACAAGCAAGAAGGTGCAGCTCATCCTCACCAACAAACCAAAGTTGATCTATGTGGACCCATCAAAGCTAATTGTGAAGGGAAATATAATATGGTCTGATAATCCAAATGATCTAAGCATCCAAGTGACTACTGCATCAAATTTCAAGATTTGCACAGTAAGCTTTCTTGACTAGTTCTTGTACAATTTCTGCGATTTATAAATATAGAAAGTAGTACATGTGAGAGTCCAAAGTTGGATTCCTAGGTGGCCATGCTAATGCTTGAAATATTTTAAGTATGTAACACCCAAGCAAATAGCAAGACCTGAAAGGGCTTTGATTTGAATTCTTTTCATGCCATATTTTTGTAAGTGATTTTCTCTAACTTGCAATACACACACACACCCCAACTCCTTCATACATAAATTTCAAGTCTTGATTCAAGTACATTTTGTGTTCCAAATTTCACACTTTTCTTTATAAATAATGTTGATGCAGCCTAAAAAGGTAATGTCGTTTGAAGATGCTAAGCAAAGAGCATGGCAGTGGAAGAAGGCAATTGAAGGACTTCAAAACCGGTGAATTTATTCTGGTTTTGAGACATATTCTTTTAGATATCCTGATTGTTCAGCAAGAAGGGGTAAAACAGTAGACTGCCCAACAATCAATTATTCATTAAGAGAAAACAAAATTGAAGATTTTGGAAGCTGGTTCTAGCTATAATTCCTCAACACAACTTAATTTTGTGATGAGTTCTTCCATCCTCTTTCATGCTTCGAAGGGATGATAAAATGTGGAAGTTCTAATTGTAGCTATGTCAAAGGTTGGAGCCAATACTTTGTAAGAAAAGATTCGTTTTTCTTTTTTTAAATTTTATATTAATATTATGAGTTGAAAGATTATATCATTTTGGTTGTCATACTGTGTGAATCATTGAATTGCTCAATTTATTGTTTCTTCAGCCCGTGGAAT